Evidence map›Paper›PMID 31413784›Full record

ArticleCardiology research2019

Spontaneous Hemorrhagic Pericardial and Pleural Effusion in a Patient Receiving Apixaban.

Michael Cinelli, Asif Uddin, Ilirjana Duka, Armaghan Soomro, Frank Tamburrino, Foad Ghavami, James Lafferty

Open access · diamondAbstract readCase Reports
In one paragraph

Article in Cardiology research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
2.1field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 19 citations in OpenAlex.

  1. The Shocking Case of a Bleeding Heart.Journal of community hospital internal medicine perspectives · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Michael CinelliDepartment of Internal Medicine, Staten Island University Hospital, Staten Island, NY, USA.
Asif UddinDepartment of Internal Medicine, Staten Island University Hospital, Staten Island, NY, USA.
Ilirjana DukaDepartment of Internal Medicine, Staten Island University Hospital, Staten Island, NY, USA.
Armaghan SoomroDepartment of Cardiology, Staten Island University Hospital, Staten Island, NY, USA.
Frank TamburrinoDepartment of Cardiology, Staten Island University Hospital, Staten Island, NY, USA.
Foad GhavamiDepartment of Cardiology, Staten Island University Hospital, Staten Island, NY, USA.
James LaffertyDepartment of Cardiology, Staten Island University Hospital, Staten Island, NY, USA.
Staten Island University Hospital · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Direct oral anticoagulants (DOACs) are used for many conditions where anticoagulation is needed such as non-valvular atrial fibrillation, deep vein thrombosis (DVT) and pulmonary embolism (PE). These novel agents have become popular since they do not require monitoring of therapeutic levels and there is a lower risk of certain bleeding complications when compared to warfarin. However, the efficacy and side effect profile of these agents have not been widely studied in certain patient cohorts, namely cancer patients and patients on immunomodulators or hormone analogs. We present a case of a patient with a history of malignancy and autoimmune disease who developed pericardial and pleural effusions shortly after initiating apixaban for treatment of a PE. In addition, we aim to increase awareness of the role that the newly available reversal agents for anticoagulants would offer in the acute management of hemorrhagic pericardial and pleural effusions caused by DOACs in patients with and without malignancy.

Indexed as

CancerCardiac tamponadeDirect acting oral anticoagulantHemopericardiumMalignancyNon-valvular atrial fibrillationPericardial effusionPulmonary embolismVenous thromboembolism

Identifiers

PMID31413784
PMCPMC6681851
OpenAlexW2965850809

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.