Evidence map›Paper›PMID 31413592›Full record

ArticleOncoTargets and therapy2019

Fasting blood glucose levels and prognosis in patients with non-small-cell lung cancer: a prospective cohort study in China.

Jin-Rong Yang, Guo-Chong Chen, Jia-Ying Xu, Chen-Jie Ling, Na Yu, Jing Yang, Da-Xiong Zeng, Min-Jing Gu, Da-Peng Li, Yu-Song Zhang and 1 more

Abstract read
In one paragraph

Article in OncoTargets and therapy, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Jin-Rong YangDepartment of Nutrition and Food Hygiene, School of Public Health, Soochow University, Suzhou 215123, People's Republic of China.
Guo-Chong ChenDepartment of Nutrition and Food Hygiene, School of Public Health, Soochow University, Suzhou 215123, People's Republic of China.
Jia-Ying XuInstitute of Quantitative Biology and Medicine, State Key Laboratory of Radiation Medicine and Protection, School of Radiation Medicine and Protection, Soochow University, Suzhou 215123, People's Republic of China.
Chen-Jie LingDepartment of Nutrition and Food Hygiene, School of Public Health, Soochow University, Suzhou 215123, People's Republic of China.
Na YuDepartment of Oncology, The Second Affiliated Hospital of Soochow University, Suzhou 215004, People's Republic of China.
Jing YangDepartment of Clinical Nutrition, The First Affiliated Hospital of Soochow University, Suzhou 215031, People's Republic of China.
Da-Xiong ZengDepartment of Respiration, The First Affiliated Hospital of Soochow University, Suzhou 215031, People's Republic of China.
Min-Jing GuDepartment of Oncology, The First Affiliated Hospital of Soochow University, Suzhou 215031, People's Republic of China.
Da-Peng LiDepartment of Oncology, The First Affiliated Hospital of Soochow University, Suzhou 215031, People's Republic of China.
Yu-Song ZhangDepartment of Oncology, The Second Affiliated Hospital of Soochow University, Suzhou 215004, People's Republic of China.
Li-Qiang QinDepartment of Nutrition and Food Hygiene, School of Public Health, Soochow University, Suzhou 215123, People's Republic of China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeNon-small-cell lung cancer (NSCLC) is the most diagnosed lung cancer and is associated with poor prognosis. This study aimed to analyze whether fasting blood glucose (FBG) levels could provide prognostic information in Chinese patients with NSCLC, using the Suzhou Lung Cancer Survival study. PATIENTS AND

methodsA prospective cohort study of adult patients with primary NSCLC was performed. The patients who were hospitalized between January 2016 and April 2018 in two hospitals affiliated with Soochow University were recruited. Patient information, including lifestyle habits and clinical and laboratory data, were collected through face-to-face interviews and evaluation of medical records. Follow-up was initiated from the date of patient enrollment until May 8, 2018 or until patient death. The long-term survival of patients was assessed every 6 months. Patient vital status was confirmed by using hospital records, telephone interview, or local death registration system. Cox proportional hazards regression was used to estimate hazard ratio and 95% confidence interval (CI) for death, with adjustment for cancer stage, medical treatments, smoking, and other potential confounders.

resultsA total of 387 patients were included in the analysis, and the numbers (percentages) of patients with stages I, II, III, and IV NSCLC were 53 (13.7%), 41 (10.6%), 64 (16.5%), and 215 (55.6%), respectively. The median duration of follow-up was 19.1 months. Compared with patients in the second tertile of FBG, the HRs for mortality were 2.16 (95% CI: 1.26-3.73) and 1.87 (95% CI: 1.03-3.42) for those in the lowest one and diabetic group, respectively. Subgroup analysis according to various patient characteristics confirmed these associations.

conclusionDiabetes and low FBG could be important predictors of death in patients with NSCLC. Maintaining appropriate blood glucose levels may improve prognosis in patients with NSCLC.

Indexed as

diabetesfasting blood glucosenon-small cell lung cancersurvival

Identifiers

PMID31413592
PMCPMC6662513

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