SynthesisVascular health and risk management2019
Prognostic implications of left ventricular strain by speckle-tracking echocardiography in the general population: a meta-analysis.
Synthesis in Vascular health and risk management, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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Who cites it
20 citing papers in PubMed, 42 citations in OpenAlex.
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- Cardiac adaptations in young triathletes: a 9-month longitudinal study during the peak height velocity period.European journal of applied physiology · 2025Article
- Haemodynamic Forces: Emerging Markers of Ventricular Remodelling in Multiple Myeloma Cardiovascular Baseline Risk Assessment.Cancers · 2024Article
- Cardiac troponin T associates with left ventricular function and synchrony assessed by CMR in the general population: results from the Akershus Cardiac Examination 1950 Study.European heart journal. Imaging methods and practice · 2024Article
- 2024 Guidelines of the Taiwan Society of Cardiology for the Diagnosis and Treatment of Heart Failure with Preserved Ejection Fraction.Acta Cardiologica Sinica · 2024Article
- Decreased diastolic hydraulic forces incrementally associate with survival beyond conventional measures of diastolic dysfunction.Scientific reports · 2023Article
- Heart Disease Characterization and Myocardial Strain Analysis in Patients withJournal of clinical medicine · 2023Article
- Feature-based clustering of the left ventricular strain curve for cardiovascular risk stratification in the general population.Frontiers in cardiovascular medicine · 2023Article
- Article
- Impact of BMIFrontiers in pediatrics · 2023Article
- Sequence and directivity in cardiac muscle injury of COVID-19 patients: an observational study.Frontiers in cardiovascular medicine · 2023Article
- Ventricular longitudinal function by cardiovascular magnetic resonance predicts cardiovascular morbidity in HFrEF patients.ESC heart failure · 2022Article
- Relationship Between Image Quality and Bias in 3D Echocardiographic Measures: Data From the SABRE (Southall and Brent Revisited) Study.Journal of the American Heart Association · 2022Observational
- Left Ventricular Strains and Myocardial Work in Adolescents With Anorexia Nervosa.Frontiers in cardiovascular medicine · 2022Article
- Automated analysis of limited echocardiograms: Feasibility and relationship to outcomes in COVID-19.Frontiers in cardiovascular medicine · 2022Article
- Prognostic Significance of Echocardiographic Measures of Cardiac Remodeling in the Community.Current cardiology reports · 2021Review
- Myocardial work in hypertensive patients with and without diabetes: An echocardiographic study.Journal of clinical hypertension (Greenwich, Conn.) · 2020Article
- Imaging Protocol, Feasibility, and Reproducibility of Cardiovascular Phenotyping in a Large Tri-Ethnic Population-Based Study of Older People: The Southall and Brent Revisited (SABRE) Study.Frontiers in cardiovascular medicine · 2020Article
- The strain and strain rate imaging paradox in echocardiography: overabundant literature in the last two decades but still uncertain clinical utility in an individual case.Archives of medical sciences. Atherosclerotic diseases · 2020Article
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 2 countries.
Funding
Abstract
purposeLeft ventricular (LV) mechanics by speckle-tracking echocardiography (STE) is prognostic in patients with cardiovascular diseases, but evidence related to community-dwelling individuals is uncertain. We therefore performed a systematic review and meta-analysis of STE as a predictor of adverse outcomes in the general population.
methodsPRISMA guidelines were followed and MEDLINE and EMBASE were searched to identify eligible studies. Primary outcome was all-cause mortality and secondary outcomes were composite cardiac and cardiovascular end-point. Random effects meta-analysis was performed, and a modified Newcastle-Ottawa Assessment Scale was used for quality assessment.
resultsEight papers matched the predefined criteria (total number of individuals studied=11,744). All publications assessed global longitudinal strain (GLS) by two-dimensional speckle-tracking echocardiography (2D-STE), one assessed circumferential, radial and transverse strains, and one assessed GLS-derived post-systolic shortening. None assessed LV rotational measures in association with outcomes. Two studies reported associations between GLS and all-cause mortality and composite cardiovascular end-point. Six papers reported an association between GLS and composite cardiac end-point, three of which were from the same study. Four papers were suitable for meta-analysis. GLS predicted all-cause mortality (pooled minimally adjusted HR per unit strain (%)=1.07 [95% CI 1.03-1.11],
conclusionsThis study provides some evidence that STE may have utility as a measure of cardiac function and risk in the general population. 2D-STE-based GLS predicts total mortality, major adverse cardiac and cardiovascular end-points in community-dwelling individuals in a limited number of studies. Despite this, this systematic review also highlights important knowledge gaps in the current literature and further evidence is needed regarding the prognostic value of LV mechanics in unselected older populations.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.