Evidence map›Paper›PMID 31413431›Full record

ArticleNigerian medical journal : journal of the Nigeria Medical Association

The Prevalence of Occult Hepatitis B Infection among Blood Donors in Lagos, Nigeria.

Akinsegun Akinbami, Mulikat Badiru, Ebele Uche, Charles Onyekwere, Kamal Ismail, Olusola Olowoselu, Esther Oluwole, Aisha Suleiman, Benjamin Augustine, Hakeem Olaosebikan

Open access · diamondAbstract read
In one paragraph

Article in Nigerian medical journal : journal of the Nigeria Medical Association. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
0.6field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it, 9 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Akinsegun AkinbamiDepartment of Haematology and Blood Transfusion, Lagos State University College of Medicine, Lagos, Nigeria.
Mulikat BadiruDepartment of Haematology and Blood Transfusion, Lagos State University College of Medicine, Lagos, Nigeria.
Ebele UcheDepartment of Haematology and Blood Transfusion, Lagos State University College of Medicine, Lagos, Nigeria.
Charles OnyekwereDepartment of Internal Medicine, Lagos State University College of Medicine, Lagos, Nigeria.
Kamal IsmailDepartment of Haematology and Blood Transfusion, Lagos State University College of Medicine, Lagos, Nigeria.
Olusola OlowoseluDepartment of Haematology and Blood Transfusion, Faculty of Clinical Sciences, College of Medicine, University of Lagos, Lagos, Nigeria.
Esther OluwoleDepartment of Community Health and Primary Care, Faculty of Clinical Sciences, College of Medicine, University of Lagos, Lagos, Nigeria.
Aisha SuleimanDepartment of Haematology and Blood Transfusion, Faculty of Basic Clinical Sciences, Ahmadu Bello University, Zaria, Nigeria.
Benjamin AugustineDepartment of Haematology and Blood Transfusion, Faculty of Basic Clinical Sciences, Ahmadu Bello University, Zaria, Nigeria.
Hakeem OlaosebikanDepartment of Internal Medicine, Lagos State University College of Medicine, Lagos, Nigeria.
Lagos State University · NGAhmadu Bello University · NGUniversity of Lagos · NG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIn occult hepatitis B virus (HBV) infection, the HBV DNA is present in the blood or liver tissue in patients negative for hepatitis B surface antigen (HBsAg) with or without anti-HBV antibodies. Thus, the absence of HBsAg in the blood only reduces the risk of transmission and is not sufficient enough to ensure the absence of HBV infection.

aimThis study was aimed at determining the prevalence of occult HBV infection among blood donors in Lagos. STUDY DESIGNS: A cross-sectional study was done among 101 consenting blood donors at Lagos State University Teaching Hospital, Ikeja, between November 2016 and January 2017. MATERIALS AND

methodsHBV DNA analysis and viral load were done at the Molecular Laboratory of National Sickle Cell Centre, Idi Araba, Lagos, for all the HBsAg negative blood donors screened by rapid kit at Ikeja.

resultsThe prevalence of occult HBV DNA among the participants was 3% consisting of 3% prevalence of HBV DNA surface antigen and 0% prevalence for precore and core of the HBV DNA.

conclusionThe low prevalence (3%) of occult HBV seen in our study does not make it cost-effective to routinely screen blood donors or the general population for HBV infection using DNA polymerase chain reaction.

Indexed as

Blood donorshepatitis B surface antigenhepatitis B virus DNA

Identifiers

PMID31413431
PMCPMC6677000
OpenAlexW2962775996

What OpenQuestion holds

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LicenceCC BY-NC-SA
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.