Evidence map›Paper›PMID 31413285›Full record

ArticleScientific reports2019

Artificial intelligence predicts the progression of diabetic kidney disease using big data machine learning.

Masaki Makino, Ryo Yoshimoto, Masaki Ono, Toshinari Itoko, Takayuki Katsuki, Akira Koseki, Michiharu Kudo, Kyoichi Haida, Jun Kuroda, Ryosuke Yanagiya and 4 more

Abstract read
In one paragraph

Article in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 104 papers, 7 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
104citing papers in PubMed, 7 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

104 citing papers in PubMed, 7 syntheses or guidelines pooled it.

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  17. Algor-Ethics in Diabetes Care: Mapping the Route.Diabetes/metabolism research and reviews · 2026
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44 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Masaki MakinoDepartment of Endocrinology and Metabolism, Fujita Health University, Toyoake, Aichi, Japan.
Ryo YoshimotoDepartment of Endocrinology and Metabolism, Fujita Health University, Toyoake, Aichi, Japan.
Masaki OnoIBM Research, Tokyo, Japan.
Toshinari ItokoIBM Research, Tokyo, Japan.
Takayuki KatsukiIBM Research, Tokyo, Japan.
Akira KosekiIBM Research, Tokyo, Japan.
Michiharu KudoIBM Research, Tokyo, Japan.
Kyoichi HaidaBusiness Process Planning Department, The Dai-ichi Life Insurance Company, Limited, Tokyo, Japan.
Jun KurodaIT Business Process Planning Department, The Dai-ichi Life Insurance Company, Limited, Tokyo, Japan.
Ryosuke YanagiyaDivision of Medical Information Systems, Fujita Health University, Toyoake, Aichi, Japan.
Eiichi SaitohDepartment of Rehabilitation Medicine, Fujita Health University, Toyoake, Aichi, Japan.
Kiyotaka HoshinagaDepartment of Urology, Fujita Health University, Toyoake, Aichi, Japan.
Yukio YuzawaDepartment of Nephrology, Fujita Health University, Toyoake, Aichi, Japan.
Atsushi SuzukiDepartment of Endocrinology and Metabolism, Fujita Health University, Toyoake, Aichi, Japan. aslapin@fujita-hu.ac.jp.ORCID http://orcid.org/0000-0003-0807-199X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Artificial intelligence (AI) is expected to support clinical judgement in medicine. We constructed a new predictive model for diabetic kidney diseases (DKD) using AI, processing natural language and longitudinal data with big data machine learning, based on the electronic medical records (EMR) of 64,059 diabetes patients. AI extracted raw features from the previous 6 months as the reference period and selected 24 factors to find time series patterns relating to 6-month DKD aggravation, using a convolutional autoencoder. AI constructed the predictive model with 3,073 features, including time series data using logistic regression analysis. AI could predict DKD aggravation with 71% accuracy. Furthermore, the group with DKD aggravation had a significantly higher incidence of hemodialysis than the non-aggravation group, over 10 years (N = 2,900). The new predictive model by AI could detect progression of DKD and may contribute to more effective and accurate intervention to reduce hemodialysis.

Indexed as

Artificial IntelligenceBig DataDisease ProgressionMachine LearningDeep LearningDiabetic NephropathiesHumansKaplan-Meier EstimateProbabilityTime Factors

Identifiers

PMID31413285
PMCPMC6694113

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.