Evidence map›Paper›PMID 31413175›Full record

ArticlemSphere2019

Quorum Sensing, Virulence, and Antibiotic Resistance of USA100 Methicillin-Resistant Staphylococcus aureus Isolates.

Morgan L Grundstad, Corey P Parlet, Jakub M Kwiecinski, Jeffrey S Kavanaugh, Heidi A Crosby, Young-Saeng Cho, Kristopher Heilmann, Daniel J Diekema, Alexander R Horswill

Open access · goldAbstract read
In one paragraph

Article in mSphere, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed
2.3field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 36 citations in OpenAlex.

  1. Article
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  9. Article
  10. AgrA directly binds to the promoter ofAntimicrobial agents and chemotherapy · 2024
    Article
  11. Anti-quorum sensing activity of poly-amidoamine dendrimer generation 5 dendrimer loaded kinase inhibitor peptide against methicillin-resistantSaudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society · 2024
    Article
  12. Microbe Interactions within the Skin Microbiome.Antibiotics (Basel, Switzerland) · 2024
    Review
  13. Review
  14. Antibiotics (Basel, Switzerland) · 2023
    Article
  15. Review
  16. Review
  17. Sub-Inhibitory Concentrations of Amoxicillin and Tylosin Affect the Biofilm Formation and Virulence ofInternational journal of environmental research and public health · 2022
    Article
  18. Article
  19. Vegetation Formation inFrontiers in cellular and infection microbiology · 2022
    Article
  20. Overview of the risks of Staphylococcus aureus infections and their control by bacteriophages and bacteriophage-encoded products.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Morgan L GrundstadUniversity of Iowa Stead Family Children's Hospital, Iowa City, Iowa, USA.
Corey P ParletDepartment of Microbiology and Immunology, University of Iowa, Iowa City, Iowa, USA.
Jakub M KwiecinskiDepartment of Immunology and Microbiology, University of Colorado School of Medicine, Aurora, Colorado, USA.ORCID 0000-0001-9472-2896
Jeffrey S KavanaughDepartment of Immunology and Microbiology, University of Colorado School of Medicine, Aurora, Colorado, USA.
Heidi A CrosbyDepartment of Immunology and Microbiology, University of Colorado School of Medicine, Aurora, Colorado, USA.
Young-Saeng ChoDepartment of Immunology and Microbiology, University of Colorado School of Medicine, Aurora, Colorado, USA.
Kristopher HeilmannDepartment of Microbiology and Immunology, University of Iowa, Iowa City, Iowa, USA.
Daniel J DiekemaDivision of Infectious Diseases, Department of Internal Medicine, University of Iowa Carver College of Medicine, Iowa City, Iowa, USA.
Alexander R HorswillDepartment of Immunology and Microbiology, University of Colorado School of Medicine, Aurora, Colorado, USA alexander.horswill@cuanschutz.edu.ORCID 0000-0002-5568-0096
University of Colorado Denver · USUniversity of Iowa · USUniversity of Iowa Stead Family Children’s Hospital · USVA Eastern Colorado Health Care System · US

Funding

Vector Core-Core 2P30DK054759 · NIDDK · UNIVERSITY OF IOWA · PI Amy Leanne Ryan · 1998 to 2026
$30.5M
RESEARCH TRAINING IN INFECTIOUS DISEASEST32AI007343 · NIAID · UNIVERSITY OF IOWA · PI STAPLETON, JACK T. · 1988 to 2024
$5.0M
Quorum Sensing Dependent Interactions with Biofilms and Innate Immunity DefensesI01BX002711 · VA · VA EASTERN COLORADO HEALTH CARE SYSTEM · PI ALEXANDER R HORSWILL · 2015 to 2026
–
BLRD VA I01 BX002711NIAID NIH HHS T32 AI007343NIDDK NIH HHS P30 DK054759
6 · The paper itself

Abstract

Methicillin-resistant

Indexed as

Drug Resistance, Multiple, BacterialQuorum SensingVirulenceAnimalsAnti-Bacterial AgentsBacterial ProteinsHumansMethicillin-Resistant Staphylococcus aureusMiceMice, Inbred BALB CMicrobial Sensitivity TestsStaphylococcal InfectionsTrans-ActivatorsVirulence FactorsAgr protein, Staphylococcus aureusAnti-Bacterial AgentsBacterial ProteinsTrans-ActivatorsVirulence FactorsagrMRSAquorum sensingUSA100

Identifiers

PMID31413175
PMCPMC6695519
OpenAlexW2967291530

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.