Evidence map›Paper›PMID 31412990›Full record

ArticleHematology, transfusion and cell therapy

The impact of multiple myeloma induction therapy on hematopoietic stem cell mobilization and collection: 25-year experience.

Amarilis Figueiredo, Rabih Kassis, Rashed Albacker, Arleigh McCurdy, Natasha Kekre, Harold Atkins

Open access · diamondAbstract read
In one paragraph

Article in Hematology, transfusion and cell therapy. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.5field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Impact of Clinical Parameters and Induction Regimens on Peripheral Blood Stem-Cell Mobilization and Collection in Multiple Myeloma Patients.Transfusion medicine and hemotherapy : offizielles Organ der Deutschen Gesellschaft fur Transfusionsmedizin und Immunhamatologie · 2023
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Amarilis FigueiredoThe Ottawa Hospital, Ottawa, Canada. Electronic address: afigueiredo@ohri.ca.
Rabih KassisThe Ottawa Hospital, Ottawa, Canada.
Rashed AlbackerCollege of Medicine King Saud University, Riyadh, Saudi Arabia.
Arleigh McCurdyThe Ottawa Hospital, Ottawa, Canada.
Natasha KekreThe Ottawa Hospital, Ottawa, Canada.
Harold AtkinsThe Ottawa Hospital, Ottawa, Canada.
Ottawa Hospital · CAKing Saud University · SA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

While first-line induction therapy for patients with multiple myeloma has changed over the years, autologous hematopoietic stem cell transplantation still plays a significant role, improving both depth of response and progression-free survival of myeloma patients. Our 25-year experience in mobilizing hematopoietic stem and progenitor cells for 472 transplant-eligible myeloma patients was retrospectively reviewed. Patients were stratified according to the remission induction therapy received, and the outcomes were compared among the cohorts that received vincristine, adriamycin and dexamethasone (VAD) (n=232), bortezomib and dexamethasone (BD) (n=86), cyclophosphamide, bortezomib and dexamethasone (CyBorD) (n=82) and other regimens (n=67). Cyclophosphamide plus granulocyte colony-stimulating factor was the predominant mobilization regimen given. A greater number of CD34

Indexed as

CyclophosphamideHematopoietic stem and progenitor cells mobilizationHematopoietic stem cells transplantationMultiple myelomaRemission induction

Identifiers

PMID31412990
PMCPMC6978537
OpenAlexW2951183316

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.