ArticleBMC medical imaging2019
Unenhanced multidetector computed tomography findings in acute central pulmonary embolism.
Article in BMC medical imaging, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed.
- Artificial intelligence in computed tomography imaging for pulmonary embolism: a narrative review from computed tomography pulmonary angiography to non-contrast computed tomography.Quantitative imaging in medicine and surgery · 2026Review
- Diagnoses of pulmonary embolism from non-contrast 4DCT using image processing-derived quantitative perfusion scores.npj biomedical innovations · 2026Article
- Transferring thrombus labels from CTPA to non-contrast CT via accurate pulmonary vessel registration: a critical step toward AI-based pulmonary embolism detection.Quantitative imaging in medicine and surgery · 2026Article
- Unenhanced CT quantitative vascular morphometry for detecting central pulmonary embolism: a multicenter study.Quantitative imaging in medicine and surgery · 2026Article
- Usefulness of electron density imaging from dual-energy CT for detecting pulmonary thromboembolism in unenhanced CT.European radiology · 2026Article
- Diagnostic Success of Non-contrast Computed Tomography Findings in Central Acute Pulmonary Thromboembolism: A Case Control Study.Thoracic research and practice · 2025Article
- The diagnostic efficacy of unenhanced CT for detecting acute central pulmonary embolism.BMC cardiovascular disorders · 2025Article
- Life-threatening pulmonary embolism seen as hyperdense clots on unenhanced CT.Jornal brasileiro de pneumologia : publicacao oficial da Sociedade Brasileira de Pneumologia e Tisilogia · 2025Article
- Improved detection of small pulmonary embolism on unenhanced computed tomography using an artificial intelligence-based algorithm - a single centre retrospective study.The international journal of cardiovascular imaging · 2024Article
- Validation of a Recently Developed Fluoroscopic Video Analysis Workstation (Radwisp™) for the Reliable Diagnosis of Acute Pulmonary Thromboembolism.Internal medicine (Tokyo, Japan) · 2024Article
- Acute pulmonary thromboembolism with high-density emboli in the pulmonary artery detected on non-enhanced computed tomography.Respirology case reports · 2024Article
- Chest non‑contrasted computed tomography in detecting acute pulmonary thromboembolism: A single‑center retrospective study.Experimental and therapeutic medicine · 2024Article
- The diagnostic potential of plasma SCUBE-1 concentration for pulmonary embolism: A pilot study.The clinical respiratory journal · 2023Article
- Evaluating the Performance of Unenhanced Computed Tomography in the Diagnosis of Pulmonary Embolism.The journal of Tehran Heart Center · 2021Article
- Hyperdense pulmonary artery sign - detection of pulmonary embolism in patients with suspected COVID-19 using non-contrast chest CT.Radiology case reports · 2021Article
- Pulmonary artery trunk enlargement on admission as a predictor of mortality in in-hospital patients with COVID-19.Japanese journal of radiology · 2021Article
- Diagnostic accuracy of X-ray versus CT in COVID-19: a propensity-matched database study.BMJ open · 2020Article
- The Predictive Value of microRNA-134 and microRNA-1233 for the Early Diagnosis of Acute Exacerbation of Chronic Obstructive Pulmonary Disease with Acute Pulmonary Embolism.International journal of chronic obstructive pulmonary disease · 2020Article
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6 authors.
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Abstract
backgroundComputed tomography pulmonary angiography (CTPA) is the gold standard for the diagnosis of pulmonary embolism (PE). However, contrast is contraindicated in some patients. The purpose of this study was to determine the diagnostic accuracy of unenhanced multidetector CT (MDCT) for diagnosis of central PE using CTPA as the gold standard.
methodsThe records of patients with suspected PE seen between 2010 and 2013 were retrospectively reviewed. Inclusion criteria were an acute, central PE confirmed by CTPA and non-enhanced MDCT before contrast injection. Patients with a PE ruled out by CTPA served as a control group. MDCT findings studied were high-attenuation emboli in pulmonary artery (PA), main PA dilatation > 33.2 mm, and peripheral wedge-shaped consolidation. Receiver operating characteristic (ROC) analysis was used to determine the sensitivity and specificity of unenhanced MDCT to detect PE. Wells score of all patients were calculated using data extracted from medical records prior to imaging analysis.
resultsThirty-two patients with a PE confirmed by CTPA and 32 with a PE ruled out by CTPA were included. Among the three main MDCT findings, high-attenuation emboli in the PA showed best diagnostic performance (Sensitivity 72.9%; Specificity 100%), followed by main PA dilatation > 33.2 mm (sensitivity 46.9%; specificity 90.6%), and peripheral wedge-shaped consolidation (sensitivity 43.8%; specificity 78.1%). Given any one or more positive findings on unenhanced MDCT, the sensitivity was 96.9% and specificity was 71.9% for a diagnosis of PE in patients. The area under the curve (AUC) of a composite measure of unenhanced MDCT findings (0.909) was significantly higher than that of the Wells score (0.688), indicating unenhanced MDCT was reliable for detecting PE than Wells score.
conclusionsUnenhanced MDCT is an alternative for the diagnosis of acute central PE when CTPA is not available.
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