Evidence map›Paper›PMID 31412789›Full record

Observational studyBMC gastroenterology2019

Water exchange colonoscopy decreased adenoma miss rates compared with literature data and local data with CO

Chi-Liang Cheng, Yen-Lin Kuo, Yu-Hsi Hsieh, Jui-Hsiang Tang, Felix W Leung

2 registry-linked trialsAbstract readComparative StudyObservational Study
PubMed Full text at PMC Publisher
In one paragraph

Observational study in BMC gastroenterology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03832322 completednot on this map

Water Exchange Colonoscopy Decreased Adenoma Miss Rates in the Right and Proximal Colon: An Observational Study Using A Tandem Colonoscopy Approach

TypeobservationalSponsorEvergreen General Hospital, TaiwanRan2018 to 2018Enrolled176ConditionsColonic Adenoma, Water Exchange ColonoscopyArmsWater exchange colonoscopy, CO2 insufflation colonoscopy
NCT04124393 nacompletednot on this map

Comparing Right Colon Adenoma and Hyperplastic Polyp Miss Rates in Colonoscopy Using Water Exchange and CO2 Insufflation: A Multicenter Randomized Tandem Study

TypeinterventionalSponsorEvergreen General Hospital, TaiwanRan2019 to 2022Enrolled386ConditionsRight Colon Adenoma Miss Rate, Right Colon Hyperplastic Polyp Miss RateArmsColon Polypectomy
3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Trial
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Chi-Liang ChengDivision of Gastroenterology, Department of Medicine, Evergreen General Hospital, 150 Huan-Zhong East Rd., Zhongli District, Taoyuan, 320, Taiwan. chiliang.cheng@gmail.com.ORCID http://orcid.org/0000-0001-6176-3210
Yen-Lin KuoDivision of Gastroenterology, Department of Medicine, Evergreen General Hospital, 150 Huan-Zhong East Rd., Zhongli District, Taoyuan, 320, Taiwan.
Yu-Hsi HsiehDivision of Gastroenterology, Dalin Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, 2 Minsheng Rd., Dalin Township, Chiayi County, 622, Taiwan.
Jui-Hsiang TangDivision of Gastroenterology and Hepatology, Department of Internal Medicine, School of Medicine, College of Medicine, Taipei Medical University, 252 Wuxing St, Xinyi District, Taipei, 100, Taiwan.
Felix W LeungDivision of Gastroenterology, Department of Medicine, Sepulveda Ambulatory Care Center, Veterans Affairs Greater Los Angeles Healthcare System and David Geffen School of Medicine at UCLA, 16111 Plummer St, North Hills, CA, 91413, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundReports showed adenoma miss rates (AMRs) of 22.5-27% in the right colon and 23.4-33.3% in the proximal colon. Missed lesions could contribute to postcolonoscopy cancers. Water exchange (WE) with near-complete removal of infused water during insertion increased adenoma detection rate but the impact on AMR had not been reported. We hypothesized that WE could reduce AMRs. Study 1 compared the AMRs of WE with literature data. Study 2 developed local AMR data with CO

methodsThe lead author attended a research seminar in 2017 on WE colonoscopy. For performance improvement, study 1 was undertaken. When data in study 1 confirmed WE produced a considerably lower AMRs in the right and proximal colon, study 2 with CO

resultsEighty-six patients completed each study. In study 1, WE removed 89% of infused water upon arrival to the cecum. The AMRs of right colon (17.5%) and proximal colon (15.5%) were considerably lower than those in the literature. Upon completion of study 2, compared with local data of CO

conclusionsWE with near-complete (89%) removal of infused water during insertion significantly decreased AMRs in the right and proximal colon compared with literature data and those of CO

trial registrationNCT03832322 (Retrospectively registered on February 2, 2019).

Indexed as

AdenomaAdultCarbon DioxideColonoscopyColorectal NeoplasmsFemaleHumansMaleMiddle AgedRetrospective StudiesWaterCarbon DioxideWaterAdenoma miss rateCarbon dioxideColonoscopyColon polypWater exchange

Identifiers

PMID31412789
PMCPMC6694537

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.