Evidence map›Paper›PMID 31412770›Full record

Trial reportBMC anesthesiology2019

Analgesic effect of the ultrasound-guided subcostal approach to transmuscular quadratus lumborum block in patients undergoing laparoscopic nephrectomy: a randomized controlled trial.

Manhua Zhu, Yong Qi, Huijuan He, Jinfeng Lou, Qingqing Pei, Yuliu Mei

Registry-linked trialOpen access · goldAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in BMC anesthesiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05191966 (Comparison of the Effects of Subcostal Anterior Quadratus Lumborum Block and Thoracic Paravertebral Block on Postoperative Acute Pain in Laparoscopic Nephrectomy Surgery), which is not on this map. Cited by 37 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed, 4 pooled it
8.6field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05191966 nacompletednot on this mapstarted 2022, after this paper: background citation

Comparison of the Effects of Subcostal Anterior Quadratus Lumborum Block and Thoracic Paravertebral Block on Postoperative Acute Pain in Laparoscopic Nephrectomy Surgery

TypeinterventionalSponsorOndokuz Mayıs UniversityRan2022 to 2023Enrolled30ConditionsAnesthesia, Analgesia, Acute Pain, Patient Controlled AnalgesiaArmsSubcostal Anterior Quadratus Lumborum Block, Thoracic Paravertebral Block
3 · Its place in the literature

Who cites it

37 citing papers in PubMed, 4 syntheses or guidelines pooled it, 71 citations in OpenAlex.

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  12. Evaluation of Analgesia Effect after Ultrasound-Guided Laparoscopic Renal Surgery.Computational and mathematical methods in medicine · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Manhua ZhuDepartment of Anesthesiology, Ningbo Medical Center Lihuili Eastern Hospital, Taipei Medical University Ningbo Medical Center, No.1111 jiangnan Road, Ningbo, Zhejiang, 315040, China.
Yong QiDepartment of Anesthesiology, Ningbo Medical Center Lihuili Eastern Hospital, Taipei Medical University Ningbo Medical Center, No.1111 jiangnan Road, Ningbo, Zhejiang, 315040, China.
Huijuan HeDepartment of Anesthesiology, Ningbo Medical Center Lihuili Eastern Hospital, Taipei Medical University Ningbo Medical Center, No.1111 jiangnan Road, Ningbo, Zhejiang, 315040, China.
Jinfeng LouDepartment of Anesthesiology, Ningbo Medical Center Lihuili Eastern Hospital, Taipei Medical University Ningbo Medical Center, No.1111 jiangnan Road, Ningbo, Zhejiang, 315040, China.
Qingqing PeiDepartment of Anesthesiology, Ningbo Beilun People's Hospital, Ningbo, Zhejiang, China, No.1288 lushan east Road, Ningbo, 315800, China.
Yuliu MeiDepartment of Anesthesiology, Ningbo Beilun People's Hospital, Ningbo, Zhejiang, China, No.1288 lushan east Road, Ningbo, 315800, China. jszhumanhua@hotmail.com.ORCID 0000-0002-3620-8044
Ningbo Medical Center Lihuili Hospital · CNUniversity of Nottingham Ningbo China · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundQuadratus lumborum block (QLB) is an effective analgesia that lowers opioid consumption after lower abdominal and hip surgeries. The subcostal approach to transmuscular QLB is a novel technique that can provide postoperative analgesia by blocking more dermatomes. The aim of this study is to evaluate the efficacy and viability of subcostal approach to QLB after laparoscopic nephrectomy.

methodsSixty patients who underwent laparoscopic nephrectomy were randomly divided into the subcostal approach to QLB group (QLB group, n = 30) and the control group (C group, n = 30). All patients underwent ultrasound-guided subcostal approach to QLB in an ipsilateral parasagittal oblique plane at the L1-L2 level. The QLB group received 0.4 cc/kg of 0.3% ropivacaine, and the C group received 0.4 cc/kg of 0.9% saline. Postoperatively, a patient-controlled intravenous analgesic pump with sufentanil was attached to all the patients. The primary outcome was sufentanil consumption within the first 24 h after surgery. The secondary outcomes included the Ramsey sedation scale (RSS) scores and Bruggemann comfort scale (BCS) scores 6 h (T1), 12 h (T2), and 24 h (T3) after surgery, intraoperative remifentanil consumption, number of patients requiring rescue analgesia, time to recovery of intestinal function, mobilization time after surgery, and presence of side effects.

resultsSufentanil consumption within the first 24 h after surgery was significantly lower in the QLB group than in the C group (mean [standard deviation]: 34.1 [9.9] μg vs 42.1 [11.6] μg, P = .006). The RSS scores did not differ between the two groups, and the BCS scores of the QLB group at T1 and T2 time points was significantly higher than those of the C group(P<0.05). The consumption of remifentanil intraoperatively and the number of patients requiring rescue analgesia were significantly lower in the QLB group (P<0.05). Time to recovery of intestinal function and mobilization time after surgery were significantly earlier in the QLB group (P<0.05). The incidence of postoperative nausea and vomiting was significantly lower in the QLB group (P<0.05).

conclusionsThe ultrasound-guided subcostal approach to QLB is an effective analgesic technique in patients undergoing laparoscopic nephrectomy as it reduces the consumption of sufentanil postoperatively.

trial registrationChiCTR1800020296 0 (Prospective registered). Initial registration date was 22/12/2018.

Indexed as

AnalgesiaAnalgesia, Patient-ControlledFemaleHumansLaparoscopyMaleMiddle AgedNephrectomyNerve BlockPain MeasurementPostoperative PainSufentanilTime FactorsUltrasonography, InterventionalSufentanilLaparoscopic nephrectomyPainPostoperativeQuadratus lumborum block

Identifiers

PMID31412770
PMCPMC6694477
OpenAlexW2966976125

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.