Evidence map›Paper›PMID 31412756›Full record

ArticleStroke2019

Infection During Delivery Hospitalization and Risk of Readmission for Postpartum Stroke.

Eliza C Miller, Timothy Wen, Mitchell S V Elkind, Alexander M Friedman, Amelia K Boehme

Open access · bronzeAbstract read
In one paragraph

Article in Stroke, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 30 citations in OpenAlex.

  1. Review
  2. Incidence, predictors, types and outcome of Post-Partum stroke: A population based study.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2025
    Article
  3. Review
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Stroke in Pregnancy: A Multidisciplinary Approach.Obstetrics and gynecology clinics of North America · 2021
    Review
  12. Review
  13. Article
  14. Observational
  15. Review
  16. Stroke Around Pregnancy; Protection and Prevention!Annals of Indian Academy of Neurology
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Eliza C MillerFrom the Department of Neurology (E.C.M., M.S.V.E., A.K.B.), Columbia University Vagelos College of Physicians and Surgeons, New York, NY.
Timothy WenDepartment of Obstetrics and Gynecology (T.W., A.M.F.), Columbia University Vagelos College of Physicians and Surgeons, New York, NY.
Mitchell S V ElkindFrom the Department of Neurology (E.C.M., M.S.V.E., A.K.B.), Columbia University Vagelos College of Physicians and Surgeons, New York, NY.
Alexander M FriedmanDepartment of Obstetrics and Gynecology (T.W., A.M.F.), Columbia University Vagelos College of Physicians and Surgeons, New York, NY.
Amelia K BoehmeFrom the Department of Neurology (E.C.M., M.S.V.E., A.K.B.), Columbia University Vagelos College of Physicians and Surgeons, New York, NY.
Columbia University · US

Funding

Institutional Career Development CoreKL2TR001874 · NCATS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI GENKINGER, JEANINE M., SHIMBO, DAICHI · 2016 to 2025
$13.6M
Neurovascular Unit Dysfunction in Women with Severe PreeclampsiaK23NS107645 · NINDS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI MILLER, ELIZA C · 2019 to 2023
$1.1M
Mentored Clinical Scientist Research Career Development AwardK08HD082287 · NICHD · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI FRIEDMAN, ALEXANDER M · 2015 to 2018
$593k
NCATS NIH HHS KL2 TR001874NICHD NIH HHS K08 HD082287NINDS NIH HHS K23 NS107645NINDS NIH HHS L30 NS103295
6 · The paper itself

Abstract

Background and Purpose- Most cases of pregnancy-related ischemic stroke (IS) and hemorrhagic stroke (HS) occur postpartum. Infections have been identified as a trigger for strokes in young people and have been associated with strokes during delivery hospitalizations, but a temporal relationship has been difficult to establish. We hypothesized that infections diagnosed during a delivery admission would be associated with an increased risk of readmission for postpartum stroke. Methods- We conducted a retrospective cohort study using the Healthcare Cost and Utilization Project's National Readmissions Database from 2010 to 2014. Using weighted survey design Poisson regression analysis, we calculated adjusted risk ratios (aRR) and 95% CI for the association between infection during delivery admission and 30-day postpartum readmission for IS or HS. Results- Out of 17.2 million delivery admissions during the study period, 2128 were readmitted within 30 days for a stroke of any type. There were 1189 HS (intracerebral hemorrhage or subarachnoid hemorrhage) and 720 IS, and the remainder unspecified pregnancy-related stroke. Adjusting for age and comorbidities, women with delivery infections were at higher risk of readmission for postpartum stroke of any type (aRR, 1.19; 95% CI, 1.01-1.41). Women with infections had higher risk of readmission for postpartum IS (aRR, 1.75; 95% CI, 1.37-2.22), but not for postpartum HS (aRR, 0.96; 95% CI, 0.75-1.23). The effect of infection on 30-day IS readmission was larger in women without hypertensive disorders of pregnancy (aRR, 2.0; 95% CI, 1.55-2.69 in women without hypertensive disorders of pregnancy versus aRR, 1.47; 95% CI, 0.9-2.38 in women with hypertensive disorders of pregnancy,

Indexed as

Pregnancy Complications, InfectiousAdultCohort StudiesFemaleHumansPatient ReadmissionPregnancyPuerperal DisordersRetrospective StudiesRisk FactorsStrokehospitalizationinfectionpostpartum periodpregnancystrokewomen

Identifiers

PMID31412756
PMCPMC6756953
OpenAlexW2967348938

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.