Evidence map›Paper›PMID 31412754›Full record

ArticleStroke2019

Sex Differences in Long-Term Quality of Life Among Survivors After Stroke in the INSTRUCT.

Hoang T Phan, Christopher L Blizzard, Mathew J Reeves, Amanda G Thrift, Dominique A Cadilhac, Jonathan Sturm, Emma Heeley, Petr Otahal, Peter Rothwell, Craig S Anderson and 5 more

Abstract read
PubMed Publisher
In one paragraph

Article in Stroke, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
39citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

39 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
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  12. Quality of life and quality-adjusted life years after stroke in Sierra Leone.International journal of stroke : official journal of the International Stroke Society · 2024
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

15 authors.

Hoang T PhanFrom the Menzies Institute for Medical Research Tasmania, University of Tasmania, Hobart, Australia (H.T.P., C.L.B., P.O., S.G.).
Christopher L BlizzardFrom the Menzies Institute for Medical Research Tasmania, University of Tasmania, Hobart, Australia (H.T.P., C.L.B., P.O., S.G.).
Mathew J ReevesDepartment of Epidemiology and Biostatistics, Michigan State University, East Lansing (M.J.R.).
Amanda G ThriftDepartment of Medicine, School of Clinical Sciences at Monash Health, Monash University, Victoria, Australia (A.G.T., D.A.C.).
Dominique A CadilhacDepartment of Medicine, School of Clinical Sciences at Monash Health, Monash University, Victoria, Australia (A.G.T., D.A.C.).
Jonathan SturmFaculty of Health and Medicine, University of Newcastle, NSW, Australia (J.S.).
Emma HeeleyGeorge Institute for Global Health, University of Sydney, NSW, Australia (E.H., C.S.A.).
Petr OtahalFrom the Menzies Institute for Medical Research Tasmania, University of Tasmania, Hobart, Australia (H.T.P., C.L.B., P.O., S.G.).
Peter RothwellStroke Prevention Research Unit, Nuffield Department of Clinical Neurosciences, John Radcliffe Hospital, Oxford, United Kingdom (P.R.).
Craig S AndersonGeorge Institute for Global Health, University of Sydney, NSW, Australia (E.H., C.S.A.).
Priya ParmarNational Institute for Stroke and Applied Neurosciences, School of Public Health and Psychosocial Studies, Auckland University of Technology, New Zealand (P.P., R.K., V.F.).
Rita KrishnamurthiNational Institute for Stroke and Applied Neurosciences, School of Public Health and Psychosocial Studies, Auckland University of Technology, New Zealand (P.P., R.K., V.F.).
Suzanne Barker-ColloSchool of Psychology, University of Auckland, New Zealand (S.B.-C.).
Valery FeiginNational Institute for Stroke and Applied Neurosciences, School of Public Health and Psychosocial Studies, Auckland University of Technology, New Zealand (P.P., R.K., V.F.).
Seana GallFrom the Menzies Institute for Medical Research Tasmania, University of Tasmania, Hobart, Australia (H.T.P., C.L.B., P.O., S.G.).

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background and Purpose- Women are reported to have poorer health-related quality of life (HRQoL) after stroke than men, but the underlying reasons are uncertain. We investigated factors contributing to the sex differences. Methods- Individual participant data on 4288 first-ever strokes (1996-2013) were obtained from 4 high-quality population-based incidence studies from Australasia and Europe. HRQoL utility scores among survivors after stroke (range from negative scores=worse than death to 1=perfect health) were calculated from 3 scales including European Quality of Life-5 Dimensions, Short-Form 6-Dimension, and Assessment of Quality of Life at 1 year (3 studies; n=1210) and 5 years (3 studies; n=1057). Quantile regression was used to estimate the median differences in HRQoL for women compared to men with adjustment for covariates. Study factors included sociodemographics, prestroke dependency, stroke-related factors (eg, stroke severity), comorbidities, and poststroke depression. Study-specific median differences were combined into pooled estimates using random-effect meta-analysis. Results- Women had lower pooled HRQoL than men (median difference

Indexed as

InternationalitySex CharacteristicsFemaleFollow-Up StudiesHumansMaleQuality of LifeStrokeSurvivorsTreatment Outcomecomorbiditydepressionincidencequality of lifesurvivors

Identifiers

PMID31412754

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.