Evidence map›Paper›PMID 31412681›Full record

SynthesisNutrients2019

Oligomeric Enteral Nutrition in Undernutrition, due to Oncology Treatment-Related Diarrhea. Systematic Review and Proposal of An Algorithm of Action.

Alejandro Sanz-Paris, María Martinez-García, Javier Martinez-Trufero, Julio Lambea-Sorrosal, Fernando Calvo-Gracia, María Elena López-Alaminos

Open access · goldAbstract readSystematic Review
In one paragraph

Synthesis in Nutrients, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
2.3field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 29 citations in OpenAlex.

  1. Trial
  2. Effect of individualized nutritional intervention on head and neck cancer patients receiving radiotherapy.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2024
    Trial
  3. Article
  4. Small Bowel Villous Atrophy in a Young Patient: A Challenging Diagnosis.GE Portuguese journal of gastroenterology · 2024
    Article
  5. Article
  6. Article
  7. Article
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  10. Article
  11. Observational
  12. Observational
  13. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Alejandro Sanz-ParisDepartment of Endocrinology and Nutrition, Miguel Servet Hospital, 50009 Zaragoza, Spain. asanzp@salud.aragon.es.
María Martinez-GarcíaDepartment of Endocrinology and Nutrition, Miguel Servet Hospital, 50009 Zaragoza, Spain.
Javier Martinez-TruferoDepartment of Oncology, Miguel Servet Hospital, 50009 Zaragoza, Spain.
Julio Lambea-SorrosalDepartment of Oncology, University Clinic Hospital, 50009 Zaragoza, Spain.
Fernando Calvo-GraciaDepartment of Endocrinology and Nutrition, University Clinic Hospital, 50009 Zaragoza, Spain.
María Elena López-AlaminosDepartment of Endocrinology and Nutrition, Miguel Servet Hospital, 50009 Zaragoza, Spain.
Hospital Universitario Miguel Servet · ESUniversidad de Zaragoza · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Oncology treatment-related diarrhea and malnutrition appear together in oncological patients because of the disease itself, or the treatments that are administered for it. Therefore it is essential to carry out a nutritional treatment. Enteral nutrition formulas, containing peptides and medium chain triglycerides, can facilitate absorption in cases of malabsorption. There are few references to the use of enteral nutrition in the clinical society guidelines of patient management with oncology treatment-related diarrhea (OTRD). A bibliographic review of the studies with oligomeric enteral nutrition in OTRD found only nine studies with chemotherapy (all with the same oligomeric formula in which oral mucositis improves, while the rest of the outcomes show different results), and eight studies with radiotherapy (with different products and very heterogeneous results). We hereby present our action algorithm to supplement the diet of OTRD patients with an oligomeric enteral nutrition formula. The first step is the nutritional assessment, followed by the assessment of the functional capacity of the patient's intestine. With these two aspects evaluated, the therapeutic possibilities available vary in degrees of complexity: These will range from the usual dietary recommendations, to supplementation with oral oligomeric enteral nutrition, along with complete enteral nutrition with oligomeric formula, and up to potentially total parenteral nutrition.

Indexed as

AlgorithmsClinical ProtocolsFood, FormulatedNutritional StatusAntineoplastic AgentsDiarrheaEnteral NutritionHumansIntestinal AbsorptionMalnutritionNutritive ValueOrganism Hydration StatusRadiation InjuriesRadiotherapyRisk FactorsTreatment OutcomeAntineoplastic Agentsnutritional algorithmoligomeric enteral nutrition formulaoncology treatment related diarrheareview

Identifiers

PMID31412681
PMCPMC6722903
OpenAlexW2968092803

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.