ArticleBiomolecules2019
The Methodological Trends of Traditional Herbal Medicine Employing Network Pharmacology.
Article in Biomolecules, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 84 papers, 1 of them a synthesis that pooled it.
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Who cites it
84 citing papers in PubMed, 1 synthesis or guideline pooled it.
- A critical assessment of Traditional Chinese Medicine databases as a source for drug discovery.Frontiers in pharmacology · 2024Pooled it
- TCM-Agent: Advancing network pharmacology and herbal medicine discovery with LLM-based multi-agent systems.Journal of pharmaceutical analysis · 2026Article
- Antitumor Study of the Miao MedicineCurrent issues in molecular biology · 2026Article
- Multiscale Interactome-Guided Prioritization of Candidate Herbs and Active Compounds for Hepatic Cirrhosis Using a Biased Random Walk Algorithm.Current issues in molecular biology · 2026Article
- Exploration of Potential Antidepressant Active Ingredients ofJournal of analytical methods in chemistry · 2026Article
- Rethinking network analysis in ethnopharmacology: a multi-omics and AI roadmap to overcome conceptual and methodological biases.Frontiers in pharmacology · 2026Article
- Multiscale Interactome-Guided Discovery Candidate Herbs and Active Ingredients Against Hyperthyroidism by Biased Random Walk Algorithm.International journal of molecular sciences · 2025Article
- Evaluating current status of network pharmacology for herbal medicine focusing on identifying mechanisms and therapeutic effects.Journal of advanced research · 2025Article
- Integrative systems biology and in-vitro analysis of cryptolepine's therapeutic role in breast cancer.Discover oncology · 2025Article
- Exploring the mechanism ofCytotechnology · 2025Article
- Exploring the Therapeutic Potential ofCurrent issues in molecular biology · 2025Article
- Rapid and cost-effective screening of therapeutic targets for isoquercitrin in insulin resistance using virtual methods and fiber SPR biosensing.Biomedical optics express · 2025Article
- Yiqi Yangyin Tongluo Recipe Alleviates Diabetic Kidney Disease Through AGE-RAGE Signalling Axis.Diabetes, metabolic syndrome and obesity : targets and therapy · 2025Article
- Investigation ofFrontiers in pharmacology · 2025Article
- Article
- A practical guide to implementing artificial intelligence in traditional East Asian medicine research.Integrative medicine research · 2024Article
- Revealing the Mechanism of Esculin in Treating Renal Cell Carcinoma Based on Network Pharmacology and Experimental Validation.Biomolecules · 2024Article
- Systematic exploration of therapeutic effects and key mechanisms of Panax ginseng using network-based approaches.Journal of ginseng research · 2024Article
- The Efficacy of Ganoderma lucidum Extracts on Treating Endometrial Cancer: A Network Pharmacology Approach.Reproductive sciences (Thousand Oaks, Calif.) · 2024Article
- Deciphering the Systemic Impact of Herbal Medicines on Allergic Rhinitis: A Network Pharmacological Approach.Life (Basel, Switzerland) · 2024Article
24 more citing papers are in PubMed but not listed here.
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Natural products, including traditional herbal medicine (THM), are known to exert their therapeutic effects by acting on multiple targets, so researchers have employed network pharmacology methods to decipher the potential mechanisms of THM. To conduct THM-network pharmacology (THM-NP) studies, researchers have employed different tools and databases for constructing and analyzing herb-compound-target networks. In this study, we attempted to capture the methodological trends in THM-NP research. We identified the tools and databases employed to conduct THM-NP studies and visualized their combinatorial patterns. We also constructed co-author and affiliation networks to further understand how the methodologies are employed among researchers. The results showed that the number of THM-NP studies and employed databases/tools have been dramatically increased in the last decade, and there are characteristic patterns in combining methods of each analysis step in THM-NP studies. Overall, the Traditional Chinese Medicine Systems Pharmacology Database and Analysis Platform (TCMSP) was the most frequently employed network pharmacology database in THM-NP studies. Among the processes involved in THM-NP research, the methodology for constructing a compound-target network has shown the greatest change over time. In summary, our analysis describes comprehensive methodological trends and current ideas in research design for network pharmacology researchers.
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