Evidence map›Paper›PMID 31412592›Full record

ArticleJournal of clinical medicine2019

Motor Evoked Potentials as Potential Biomarkers of Early Atypical Corticospinal Tract Development in Infants with Perinatal Stroke.

Jesse L Kowalski, Samuel T Nemanich, Tanjila Nawshin, Mo Chen, Colleen Peyton, Elizabeth Zorn, Marie Hickey, Raghavendra Rao, Michael Georgieff, Kyle Rudser and 1 more

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05013736 (Perinatal Stroke), which is not on this map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05013736 recruitingnot on this mapstarted 2022, after this paper: background citation

Perinatal Stroke: Longitudinal Assessment of Infant Brain Organization and Recovery Through Neuroexcitability, Neuroimaging and Motor Development

TypeobservationalSponsorUniversity of Wisconsin, MadisonRan2022 to 2026Enrolled65ConditionsPerinatal StrokeArmsMagnetic Resonance Imaging, Behavioral Assessments, Non invasive Transcranial Magnetic Stimulation
3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 27 citations in OpenAlex.

  1. Trial
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  9. Development of the Ontogenetic Self-Regulation Clock.International journal of molecular sciences · 2022
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Jesse L KowalskiDepartment of Rehabilitation Medicine, University of Minnesota, Minneapolis, MN 55455, USA.ORCID 0000-0003-1745-3877
Samuel T NemanichDepartment of Rehabilitation Medicine, University of Minnesota, Minneapolis, MN 55455, USA.ORCID 0000-0001-6093-7266
Tanjila NawshinDepartment of Rehabilitation Medicine, University of Minnesota, Minneapolis, MN 55455, USA.
Mo ChenDepartment of Psychiatry, University of Minnesota, Minneapolis, MN 55455, USA.
Colleen PeytonDepartment of Physical Therapy and Human Movement Sciences, Northwestern University, Chicago, IL 60611, USA.
Elizabeth ZornDivision of Neonatology, Children's Hospitals and Clinics of Minnesota, Minneapolis, MN 55455, USA.
Marie HickeyDepartment of Pediatrics, University of Minnesota, Minneapolis, MN 55455, USA.
Raghavendra RaoDepartment of Pediatrics, University of Minnesota, Minneapolis, MN 55455, USA.ORCID 0000-0002-6089-5972
Michael GeorgieffDepartment of Pediatrics, University of Minnesota, Minneapolis, MN 55455, USA.
Kyle RudserDivision of Biostatistics, University of Minnesota, Minneapolis, MN 55455, USA.
Bernadette T GillickDepartment of Rehabilitation Medicine, University of Minnesota, Minneapolis, MN 55455, USA. gillick@umn.edu.
University of Minnesota · USChildren’s Minnesota - St. Paul Hospital · USNorthwestern University · US

Funding

University of Minnesota Clinical and Translational Science Institute (UMN CTSI)UL1TR002494 · NCATS · UNIVERSITY OF MINNESOTA · PI BLAZAR, BRUCE R, WEISDORF, DANIEL J · 2018 to 2022
$34.9M
Techniques DevelopmentP2CHD086844 · NICHD · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI GEORGE, MARK S · 2015 to 2024
$12.7M
NMR Imaging and SpectroscopyP41EB015894 · NIBIB · UNIVERSITY OF MINNESOTA · PI UGURBIL, KAMIL · 2012 to 2017
$8.4M
Cerebral Palsy Alliance Research Foundation N/AFoundation for Physical Therapy Florence P. Kendall ScholarshipNCATS NIH HHS UL1 TR002494NIBIB NIH HHS P41 EB015894NICHD NIH HHS P2C HD086844NIH HHS HD078484-01A1the University of Minnesota Center for Magnetic Resonance Research 1S10OD017974-01the University of Minnesota Clinical and Translational Science Institute (National Center for Advancing Translational Sciences of the National Institutes of Health) UL1TR002494
6 · The paper itself

Abstract

Diagnosis of cerebral palsy (CP) after perinatal stroke is often delayed beyond infancy, a period of rapid neuromotor development with heightened potential for rehabilitation. This study sought to assess whether the presence or absence of motor evoked potentials (MEPs) elicited by transcranial magnetic stimulation (TMS) could be an early biomarker of atypical development within the first year of life. In 10 infants with perinatal stroke, motor outcome was assessed with a standardized movement assessment. Single-pulse TMS was utilized to assess presence of MEPs. Younger infants (3-6 months CA,

Indexed as

cerebral palsyinfantnon-invasive brain stimulationpediatricsperinatal stroketranscranial magnetic stimulation

Identifiers

PMID31412592
PMCPMC6723226
OpenAlexW2969100393

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.