Evidence map›Paper›PMID 31412538›Full record

ArticleInternational journal of molecular sciences2019

Ether Lipid Deficiency in Mice Produces a Complex Behavioral Phenotype Mimicking Aspects of Human Psychiatric Disorders.

Fabian Dorninger, Anna Gundacker, Gerhard Zeitler, Daniela D Pollak, Johannes Berger

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
3.0field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 39 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Bifunctional Probes Reveal the Rules of Intracellular Ether Lipid Transport.Angewandte Chemie (International ed. in English) · 2025
    Article
  5. Article
  6. Effect of Sphingomyelin and Vitamin D3 Intake on the Rabbit Brain.International journal of molecular sciences · 2025
    Article
  7. Article
  8. Review
  9. Review
  10. Synthesis of ether lipids: natural compounds and analogues.Beilstein journal of organic chemistry · 2023
    Review
  11. Article
  12. Article
  13. Review
  14. AFrontiers in cell and developmental biology · 2022
    Article
  15. Article
  16. Review
  17. Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Fabian DorningerDepartment of Pathobiology of the Nervous System, Center for Brain Research, Medical University of Vienna, Spitalgasse 4, 1090 Vienna, Austria.ORCID 0000-0003-0852-1524
Anna GundackerDepartment of Neurophysiology and Neuropharmacology, Center for Physiology and Pharmacology, Medical University of Vienna, Schwarzspanierstraße 17, 1090 Vienna, Austria.
Gerhard ZeitlerDepartment of Pathobiology of the Nervous System, Center for Brain Research, Medical University of Vienna, Spitalgasse 4, 1090 Vienna, Austria.
Daniela D PollakDepartment of Neurophysiology and Neuropharmacology, Center for Physiology and Pharmacology, Medical University of Vienna, Schwarzspanierstraße 17, 1090 Vienna, Austria. daniela.pollak@meduniwien.ac.at.
Johannes BergerDepartment of Pathobiology of the Nervous System, Center for Brain Research, Medical University of Vienna, Spitalgasse 4, 1090 Vienna, Austria. johannes.berger@meduniwien.ac.at.ORCID 0000-0003-0182-2658
Medical University of Vienna · AT

Funding

Austrian Science Fund FWF DOC 33Austrian Science Fund FWF I 2738Austrian Science Fund FWF P 24843Austrian Science Fund FWF P 31082
6 · The paper itself

Abstract

Ether lipids form a specialized subgroup of phospholipids that requires peroxisomes to be synthesized. We have previously detected that deficiency in these lipids leads to a severe disturbance of neurotransmitter homeostasis and release as well as behavioral abnormalities, such as hyperactivity, in a mouse model. Here, we focused on a more detailed examination of the behavioral phenotype of ether lipid-deficient mice (

Indexed as

Behavior, AnimalPhenotypeAnimalsDisease Models, AnimalHumansMaze LearningMental DisordersMiceMice, KnockoutNeurotransmitter AgentsPeroxisomesPhospholipid EthersPhospholipidsSocial BehaviorNeurotransmitter AgentsPhospholipid EthersPhospholipidsAlzheimer’s diseaseautismbehaviorether phospholipidmemoryneurotransmissionperoxisomeplasmalogensocial interactionsynapse

Identifiers

PMID31412538
PMCPMC6720005
OpenAlexW2967741941

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.