SynthesisCaries research2019
How to Intervene in the Root Caries Process? Systematic Review and Meta-Analyses.
Synthesis in Caries research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 5 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
29 citing papers in PubMed, 5 syntheses or guidelines pooled it, 71 citations in OpenAlex.
- Caries prevention in permanent teeth - basic recommendations of the German S 3 guideline.Clinical oral investigations · 2026Guideline
- Root Cementum Molecular Structure and Its Role in Maintaining Oral Health-Systematic Review.International journal of molecular sciences · 2025Pooled it
- Direct Composite Restorations on Permanent Teeth in the Anterior and Posterior Region - An Evidence-Based Clinical Practice Guideline - Part 1: Indications for Composite Restorations.The journal of adhesive dentistry · 2024Guideline
- Systematic review and meta-analysis on physical barriers to prevent root dentin demineralization.Scientific reports · 2022Pooled it
- Tests to detect and inform the diagnosis of root caries.The Cochrane database of systematic reviews · 2020Pooled it
- Enhancing Intraoral Fluoride Retention in Older Adults: A Randomized Crossover Study.JDR clinical and translational research · 2025Trial
- How do carious root lesions develop after the end of professional preventive measures?-Preliminary findings of a randomized clinical trial.Odontology · 2022Trial
- Effect of moisture control on root caries progression adjacent to different restorative materials in an in-vitro biofilm model.Odontology · 2026Article
- Coronal and Root Caries in Older Adults: Associated Factors, Quality of Life Impact, and Treatment-A Scoping Review.Gerodontology · 2026Article
- Efficacy of topical strategies to prevent the onset of root caries lesions: an in vitro study.Odontology · 2026Article
- Neutrophil activity compromises root caries remineralization and alters caries-affected-like dentin.Clinical oral investigations · 2025Article
- Frontiers of Global Research Trend on Root Caries: A Bibliometric Analysis.International dental journal · 2024Review
- Minimum intervention oral care: staging and grading dental carious lesions in clinical practice.British dental journal · 2024Article
- Veillonella parvula promotes root caries development through interactions with Streptococcus mutans and Candida albicans.Microbial biotechnology · 2024Article
- Comparative analysis of microbiome in coronal and root caries.BMC oral health · 2024Article
- ORCA-EFCD consensus report on clinical recommendation for caries diagnosis. Paper I: caries lesion detection and depth assessment.Clinical oral investigations · 2024Article
- The Older Adults' Intention to Use Silver Diamine Fluoride for Dental Caries Treatment.Clinical, cosmetic and investigational dentistry · 2024Article
- Article
- The action of microbial collagenases in dentinal matrix degradation in root caries and potential strategies for its management: a comprehensive state-of-the-art review.Journal of applied oral science : revista FOB · 2024Review
- Changes in Gloss Alteration, Surface Roughness, and Color of Direct Dental Restorative Materials after Professional Dental Prophylaxis.Journal of functional biomaterials · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 3 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The aim of this review as part of the preparation for a workshop organized by the European Federation of Conservative Dentistry (EFCD) in conjunction with the European Organisation for Caries Research (ORCA) was to systematically analyze available evidence of non-, micro- as well as invasive interventions for root caries lesions (RCLs). For each treatment strategy, a separate systematic review was either performed (micro-invasive and choice of restorative material) or updated (non-invasive and excavation technique) each of them following PRISMA guidelines, and if possible meta-analyses were performed. Besides the general advice to improve tooth brushing with fluoride toothpaste main findings for non-invasive interventions in RCLs, the use of dentifrices containing 5,000 ppm F- as well as professionally applied chlorhexidine varnish or silver diamine fluoride seemed to be more efficacious to arrest root caries compared to conventional fluoride toothpaste or placebo respectively. However, this conclusion is based only on a few randomized clinical trials. For micro-invasive treatments, only 2 studies focusing on sealants were available without clear conclusions. A recent review on the comparison of atraumatic restorative treatment compared with conventional treatment concluded that there is insufficient data to clearly rule out if any difference with regard to restoration longevity between both techniques exists. When restoring coventionally, composites performed better than resin-modified and glass ionomer cements. However, all materials showed rather high annual failure rates in the majority of the studies and evidence is based on a low number of prospective studies with a rather high risk of bias.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.