Evidence map›Paper›PMID 31411686›Full record

ArticleDatabase : the journal of biological databases and curation2019

CasPDB: an integrated and annotated database for Cas proteins from bacteria and archaea.

Zhongjie Tang, ShaoQi Chen, Ang Chen, Bifang He, Yuwei Zhou, Guoshi Chai, FengBiao Guo, Jian Huang

Open access · goldAbstract read
In one paragraph

Article in Database : the journal of biological databases and curation, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
0.5field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 23 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Genomic footprint of a shared Type 5 prophage inApplied and environmental microbiology · 2025
    Article
  4. Article
  5. Review
  6. Review
  7. Enzyme Databases in the Era of Omics and Artificial Intelligence.International journal of molecular sciences · 2023
    Review
  8. Article
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Zhongjie TangCenter for Informational Biology, University of Electronic Science and Technology of China, Chengdu 611731, China.
ShaoQi ChenCenter for Informational Biology, University of Electronic Science and Technology of China, Chengdu 611731, China.
Ang ChenCenter for Informational Biology, University of Electronic Science and Technology of China, Chengdu 611731, China.
Bifang HeCenter for Informational Biology, University of Electronic Science and Technology of China, Chengdu 611731, China.
Yuwei ZhouCenter for Informational Biology, University of Electronic Science and Technology of China, Chengdu 611731, China.
Guoshi ChaiCenter for Informational Biology, University of Electronic Science and Technology of China, Chengdu 611731, China.
FengBiao GuoCenter for Informational Biology, University of Electronic Science and Technology of China, Chengdu 611731, China.
Jian HuangCenter for Informational Biology, University of Electronic Science and Technology of China, Chengdu 611731, China.
University of Electronic Science and Technology of China · CNGuizhou University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Clustered regularly interspaced short palindromic repeats (CRISPR) and associated proteins (Cas) constitute CRISPR-Cas systems, which are antiphage immune systems present in numerous bacterial and most archaeal species. In recent years, CRISPR-Cas systems have been developed into reliable and powerful genome editing tools. Nevertheless, finding similar or better tools from bacteria or archaea remains crucial. This requires the exploration of different CRISPR systems, identification and characterization new Cas proteins. Archives tailored for Cas proteins are urgently needed and necessitate the prediction and grouping of Cas proteins into an information center with all available experimental evidence. Here, we constructed Cas Protein Data Bank (CasPDB), an integrated and annotated online database for Cas proteins from bacteria and archaea. The CasPDB database contains 287 reviewed Cas proteins, 257 745 putative Cas proteins and 3593 Cas operons from 32 023 bacteria species and 1802 archaea species. The database can be freely browsed and searched. The CasPDB web interface also represents all the 3593 putative Cas operons and its components. Among these operons, 328 are members of the type II CRISPR-Cas system.

Indexed as

CRISPR-Cas SystemsDatabases, ProteinArchaeaArchaeal ProteinsBacteriaBacterial ProteinsCRISPR-Associated ProteinsArchaeal ProteinsBacterial ProteinsCRISPR-Associated Proteins

Identifiers

PMID31411686
PMCPMC6693189
OpenAlexW2968536921

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.