ArticleeLife2019
A genetic selection reveals functional metastable structures embedded in a toxin-encoding mRNA.
Article in eLife, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
14 citing papers in PubMed, 18 citations in OpenAlex.
- Long-range mRNA folding shapes expression and sequence of bacterial genes.Molecular cell · 2026Article
- The role of toxin-antitoxin systems inJournal of bacteriology · 2026Review
- An RNA structural switch controlling bacterial toxin translation.Nucleic acids research · 2026Article
- Type I toxin-antitoxin systems in bacteria: from regulation to biological functions.EcoSal Plus · 2024Review
- Disentangling the pseudoknots of toxin translation.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- An RNA pseudoknot mediates toxin translation and antitoxin inhibition.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- Profiling the intragenic toxicity determinants of toxin-antitoxin systems: revisiting hok/Sok regulation.Nucleic acids research · 2023Article
- Transcription complexes as RNA chaperones.Transcription · 2021Article
- CoBold: a method for identifying different functional classes of transient RNA structure features that can impact RNA structure formation in vivo.Nucleic acids research · 2021Article
- RNA Regulated Toxin-Antitoxin Systems in Pathogenic Bacteria.Frontiers in cellular and infection microbiology · 2021Review
- Riboregulation in the Major Gastric PathogenFrontiers in microbiology · 2021Review
- A peptide of a type I toxin-antitoxin system inducesProceedings of the National Academy of Sciences of the United States of America · 2020Article
- How Many Messenger RNAs Can Be Translated by the START Mechanism?International journal of molecular sciences · 2020Article
- Structural Alignment and Covariation Analysis of RNA Sequences.Bio-protocol · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 1 institution in 1 country.
Funding
Abstract
Post-transcriptional regulation plays important roles to fine-tune gene expression in bacteria. In particular, regulation of type I toxin-antitoxin (TA) systems is achieved through sophisticated mechanisms involving toxin mRNA folding. Here, we set up a genetic approach to decipher the molecular underpinnings behind the regulation of a type I TA in
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.