Evidence map›Paper›PMID 31411277›Full record

ArticleClinics (Sao Paulo, Brazil)2019

Impact of heart rate on reproducibility of heart rate variability analysis in the supine and standing positions in healthy men.

Carlos Janssen Gomes da Cruz, Luiz Guilherme Grossi Porto, Paloma da Silva Rolim, Deleon de Souza Pires, Giliard Lago Garcia, Guilherme Eckhardt Molina

Abstract readEvaluation Study
In one paragraph

Article in Clinics (Sao Paulo, Brazil), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it.

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  5. Evaluation of Small-Molecule Candidates as Modulators of M-Type KInternational journal of molecular sciences · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Carlos Janssen Gomes da CruzGrupo de Estudos e Pesquisas em Funcao Autonomica Cardiaca (GEFAC), Centro Universitario Euro Americano - UNIEURO, Brasilia, DF, BR.ORCID 0000-0002-5879-8102
Luiz Guilherme Grossi PortoLaboratorio de Fisiologia do Exercicio, Faculdade de Educacao Fisica, Universidade de Brasilia, Brasilia, DF, BR.ORCID 0000-0002-6240-1614
Paloma da Silva RolimGrupo de Estudos e Pesquisas em Funcao Autonomica Cardiaca (GEFAC), Centro Universitario Euro Americano - UNIEURO, Brasilia, DF, BR.ORCID 0000-0003-2674-5345
Deleon de Souza PiresGrupo de Estudos e Pesquisas em Funcao Autonomica Cardiaca (GEFAC), Centro Universitario Euro Americano - UNIEURO, Brasilia, DF, BR.ORCID 0000-0002-4509-2055
Giliard Lago GarciaLaboratorio de Fisiologia do Exercicio, Faculdade de Educacao Fisica, Universidade de Brasilia, Brasilia, DF, BR.ORCID 0000-0002-2340-4054
Guilherme Eckhardt MolinaLaboratorio de Fisiologia do Exercicio, Faculdade de Educacao Fisica, Universidade de Brasilia, Brasilia, DF, BR.ORCID 0000-0002-5937-079X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThe reliability of heart rate variability (HRV) analysis is not yet fully understood, especially considering different body positions and the mathematical influence of heart rate. The aim of this study was to evaluate the reliability of HRV in supine and standing positions, with and without mathematical adjustment of HRV by the average R-R interval (iRR).

methodsWe evaluated 37 young males (23.1±4 years; 25.1±3 kg/m2). A 5-min segment of the iRR was collected in the supine and standing positions on three occasions separated by 48-hour intervals. Absolute and relative reliability of temporal and spectral indices were assessed by the coefficient of variation (CV) and the intraclass correlation coefficient (ICC), respectively.

resultsWe did not observe differences in HRV indices in the three occasions in the supine or standing position (p>0.05). Moderate to good reproducibility was observed for temporal and spectral indices of HRV in the supine position (ICC: 0.65-0.89; CV: 0.9-19.8). In the orthostatic position, low to good reproducibility was observed (ICC: 0.35-0.89; CV: 1.1-34.8), with higher ICCs for temporal indices. After mathematical adjustment, only a small modification in HRV reliability was observed in both positions.

conclusionsIn young adult males, the mathematical adjustment of HRV by the average iRR led to a nonsignificant effect on HRV reliability. Additionally, HRV reliability is dependent on body position and the index analyzed. Promising measures in both supine and standing positions include r-MSSD and the HF band (parasympathetic indices).

Indexed as

Standing PositionAdultBody Mass IndexHeart RateHumansMaleModels, TheoreticalReference ValuesReproducibility of ResultsStatistics, NonparametricSupine PositionYoung Adult

Identifiers

PMID31411277
PMCPMC6683304

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.