Evidence map›Paper›PMID 31411106›Full record

ArticleChild neuropsychology : a journal on normal and abnormal development in childhood and adolescence2020

Effect of READ1 on latent profiles of reading disorder and comorbid attention and language impairment subtypes.

Miao Li, Dongnhu T Truong, Mellissa DeMille, Jeffrey G Malins, Maureen W Lovett, Joan Bosson-Heenan, Jeffrey R Gruen, Jan C Frijters

Open access · bronzeAbstract read
In one paragraph

Article in Child neuropsychology : a journal on normal and abnormal development in childhood and adolescence, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.6field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 2 countries.

Miao LiDepartment of Curriculum and Instruction, College of Education, University of Houston, Houston, TX, USA.
Dongnhu T TruongDepartments of Pediatrics and Genetics, Yale University School of Medicine, New Haven, CT, USA.
Mellissa DeMilleDepartments of Pediatrics and Genetics, Yale University School of Medicine, New Haven, CT, USA.
Jeffrey G MalinsDepartments of Pediatrics and Genetics, Yale University School of Medicine, New Haven, CT, USA.
Maureen W LovettNeurosciences & Mental Health Program, The Hospital for Sick Children, Toronto, Ontario, Canada.
Joan Bosson-HeenanDepartments of Pediatrics and Genetics, Yale University School of Medicine, New Haven, CT, USA.
Jeffrey R GruenDepartments of Pediatrics and Genetics, Yale University School of Medicine, New Haven, CT, USA.
Jan C FrijtersDepartment of Child and Youth Studies, Brock University, St. Catharines, Ontario, Canada.
Yale University · USPediatrics and Genetics · USBrock University · CAHospital for Sick Children · CAUniversity of Houston · US

Funding

VALIDITY OF SUBTYPES OF ADHDP50HD027802 · NICHD · UNIVERSITY OF COLORADO AT BOULDER · PI ERIK G WILLCUTT · 1990 to 2026
$44.9M
Molecular Genetic Examination of Co-Occurring Learning DisabilitiesK99HD094902 · NICHD · YALE UNIVERSITY · PI TRUONG, DONGNHU T · 2018 to 2019
$202k
NICHD NIH HHS K99 HD094902NICHD NIH HHS P50 HD027802
6 · The paper itself

Abstract

Recent studies of co-occurring reading disorder (RD) and attention deficit/hyperactivity disorder (ADHD), and co-occurring RD and language impairment (LI), support a core disability plus co-occurrence model focused on language and attention. Genetic factors have been associated with poor reading performance. However, little is known about whether different genetic variants independently contribute to RD co-occurrence subtypes. We aimed to identify subgroups of struggling readers using a latent profile analysis (LPA) in a sample of 1,432 Hispanic American and African American youth. RD classes were then tested for association with variants of READ1, a regulatory element within the candidate RD risk gene,

Indexed as

AdolescentAllelesAttentionAttention Deficit Disorder with HyperactivityChildComorbidityDyslexiaFemaleHumansLanguageLanguage Development DisordersLearning DisabilitiesMaleMicrotubule-Associated ProteinsReadingDCDC2 protein, humanMicrotubule-Associated Proteinsattention deficit/hyperactivity disorder; language impairmentDCDC2Genetic associationREAD1reading disorder

Identifiers

PMID31411106
PMCPMC8163097
OpenAlexW2969153152

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.