Evidence map›Paper›PMID 31411060›Full record

ArticleAmerican journal of physiology. Lung cellular and molecular physiology2019

Surfactant protein-D modulation of pulmonary macrophage phenotype is controlled by

Chang-Jiang Guo, Elena N Atochina-Vasserman, Elena Abramova, Ley Cody Smith, Michael F Beers, Andrew J Gow

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in American journal of physiology. Lung cellular and molecular physiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.2field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 10 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
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  5. Review
  6. Observational
  7. Article
  8. American journal of physiology. Lung cellular and molecular physiology · 2019
    Article
4 · The record

Corrections and comments

  • Commented on by
    2019
5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Chang-Jiang GuoEnvironmental and Occupational Health Sciences Institute, Rutgers, The State University of New Jersey, Piscataway, New Jersey.
Elena N Atochina-VassermanSchool of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania.
Elena AbramovaEnvironmental and Occupational Health Sciences Institute, Rutgers, The State University of New Jersey, Piscataway, New Jersey.
Ley Cody SmithEnvironmental and Occupational Health Sciences Institute, Rutgers, The State University of New Jersey, Piscataway, New Jersey.
Michael F BeersSchool of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania.ORCID 0000-0002-2149-3209
Andrew J GowEnvironmental and Occupational Health Sciences Institute, Rutgers, The State University of New Jersey, Piscataway, New Jersey.
Rutgers, The State University of New Jersey · USUniversity of Pennsylvania · US

Funding

Translational Research Support CoreP30ES013508 · NIEHS · UNIVERSITY OF PENNSYLVANIA · PI Trevor M Penning · 2006 to 2026
$35.3M
TRAINING IN EVIRONMENTAL TOXICOLOGYT32ES007148 · NIEHS · RUTGERS THE ST UNIV OF NJ NEW BRUNSWICK · PI Lauren M Aleksunes · 1987 to 2026
$11.4M
Models of P. carinii infections SP-A and SP-D null miceR01HL064520 · NHLBI · UNIVERSITY OF PENNSYLVANIA · PI BEERS, MICHAEL FRANCIS · 1999 to 2009
$3.3M
NO-Modified Biomolecules and Pulmonary SignalingR01HL086621 · NHLBI · RUTGERS, THE STATE UNIV OF N.J. · PI GOW, ANDREW J · 2008 to 2016
$2.8M
Ozone toxicity: targeting the resolution of inflammationF32ES030984 · NIEHS · RUTGERS, THE STATE UNIV OF N.J. · PI SMITH, LEY C · 2019 to 2019
$64k
NHLBI NIH HHS R01 HL064520NHLBI NIH HHS R01 HL086621NIEHS NIH HHS F32 ES030984NIEHS NIH HHS P30 ES013508NIEHS NIH HHS T32 ES007148
6 · The paper itself

Abstract

Surfactant protein-D (SP-D) is a regulator of pulmonary innate immunity whose oligomeric state can be altered through

Indexed as

Protein Processing, Post-TranslationalAnimalsBronchoalveolar Lavage FluidChemokine CCL20Chemokine CXCL1Cyclooxygenase 2FemaleImmunity, InnateInterleukin-1betaLipopolysaccharidesLungMacrophages, AlveolarMaleMiceMice, Inbred C57BLNF-kappa BCCL20 protein, mouseChemokine CCL20Chemokine CXCL1Cxcl1 protein, mouseCyclooxygenase 2IL1B protein, mouseInterleukin-1betaLipopolysaccharidesNF-kappa BNitric Oxide Synthase Type IINitroso CompoundsNos2 protein, mousePtgs2 protein, mousePulmonary Surfactant-Associated Protein DTumor Necrosis Factor-alphaVascular Cell Adhesion Molecule-1inducible nitric oxide synthasemacrophage phenotypepneumocystis pneumoniaS-nitrosothiolsurfactant protein-D

Identifiers

PMID31411060
PMCPMC6957369
OpenAlexW2969068760

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.