Evidence map›Paper›PMID 31411024›Full record

ArticleChemical research in toxicology2019

Engineering Dynamic Surface Peptide Networks on Butyrylcholinesterase

Kirstin P Hester, Krishna Bhattarai, Haobo Jiang, Pratul K Agarwal, Carey Pope

Abstract read
In one paragraph

Article in Chemical research in toxicology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Kirstin P HesterDepartment of Physiological Sciences , Oklahoma State University , Stillwater , Oklahoma 74078 , United States.
Krishna BhattaraiDepartment of Entomology and Plant Pathology , Oklahoma State University , Stillwater , Oklahoma 74078 , United States.
Haobo JiangDepartment of Entomology and Plant Pathology , Oklahoma State University , Stillwater , Oklahoma 74078 , United States.
Pratul K AgarwalDepartment of Biochemistry & Cellular and Molecular Biology , University of Tennessee , Knoxville , Tennessee 37996 , United States.ORCID 0000-0002-3848-9492
Carey PopeDepartment of Physiological Sciences , Oklahoma State University , Stillwater , Oklahoma 74078 , United States.ORCID 0000-0001-9936-3589

Funding

The Effect of Pesticide Exposure on Cognitive and Brain Development in Latino Children: PACE5 Administrative Supplement 2R01ES008739 · NIEHS · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI ARCURY, THOMAS A., LAURIENTI, PAUL · 2000 to 2022
$11.1M
Initiation and Regulation of Prophenoloxidase ActivationR01GM058634 · NIGMS · OKLAHOMA STATE UNIVERSITY STILLWATER · PI JIANG, HAOBO · 1999 to 2022
$4.0M
Conformational sub-states in enzyme catalysis: Applications to ribonucleaseR01GM105978 · NIGMS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI AGARWAL, PRATUL K, DOUCET, NICOLAS · 2014 to 2018
$2.8M
Activation and catalytic mechanisms of mosquito phenoloxidasesR21AI139998 · NIAID · OKLAHOMA STATE UNIVERSITY STILLWATER · PI JIANG, HAOBO · 2018 to 2019
$402k
Prophenoloxidases of Anopheles gambiaeR21AI112662 · NIAID · OKLAHOMA STATE UNIVERSITY STILLWATER · PI JIANG, HAOBO · 2014 to 2015
$381k
NIAID NIH HHS R21 AI112662NIAID NIH HHS R21 AI139998NIEHS NIH HHS R01 ES008739NIGMS NIH HHS R01 GM058634NIGMS NIH HHS R01 GM105978
6 · The paper itself

Abstract

The single residue mutation of butyrylcholinesterase (BChE

Indexed as

BiocatalysisButyrylcholinesteraseCatalytic DomainCholinesterase InhibitorsEchothiophate IodideHydrolysisIsoflurophateKineticsMolecular Dynamics SimulationMutationParaoxonProtein BindingProtein EngineeringThermodynamicsButyrylcholinesteraseCholinesterase InhibitorsEchothiophate IodideIsoflurophateParaoxon

Identifiers

PMID31411024
PMCPMC7251593

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.