Evidence map›Paper›PMID 31411011›Full record

ArticleJournal of biomedical optics2019

Optical coherence tomography-guided dynamic focusing for combined optical and mechanical scanning multimodal photoacoustic microscopy.

Arash Dadkhah, Shuliang Jiao

Abstract read
In one paragraph

Article in Journal of biomedical optics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Arash DadkhahFlorida International University, Department of Biomedical Engineering, Miami, Florida, United States.
Shuliang JiaoFlorida International University, Department of Biomedical Engineering, Miami, Florida, United States.

Funding

Imaging the functional biomarker of photoreceptorsR01EY026643 · NEI · FLORIDA INTERNATIONAL UNIVERSITY · PI JIAO, SHULIANG · 2017 to 2020
$1.9M
NEI NIH HHS R01 EY026643
6 · The paper itself

Abstract

To achieve fast imaging and large field of view (FOV), we improved our multimodal imaging system, which integrated optical resolution photoacoustic microscopy, optical coherence tomography (OCT), and confocal fluorescence microscopy in one platform, by combining optical scanning with mechanical scanning. To ensure good focusing of the objective lens over all the imaged area, we employed OCT-guided dynamic focusing. Different from our previous point-by-point dynamic focusing, we employed an area-by-area focusing adjustment strategy, in which each fast optical scanning area has a fixed focusing depth. We have demonstrated the performance of the system by imaging biological samples ex vivo (plant leaf) and in vivo (mouse ear). The system has achieved uniform resolution in an FOV of 10  mm  ×  10  mm with an imaging time of about 5 min.

Indexed as

Microscopy, ConfocalPhotoacoustic TechniquesPlant LeavesTomography, Optical CoherenceAnimalsEarMiceModels, StatisticalMultimodal ImagingSignal-To-Noise Ratioconfocal fluorescence microscopydynamic focusingmultimodal imagingoptical coherence tomographyoptical coherence tomography guidancephotoacoustic microscopy

Identifiers

PMID31411011
PMCPMC7005572

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.