Evidence map›Paper›PMID 31410985›Full record

ArticleJournal of cellular and molecular medicine2019

Deregulated lncRNA expression profile in the mouse lung adenocarcinomas with KRAS-G12D mutation and P53 knockout.

Meiqin Zhang, Nan Jiang, Renjie Cui, Sichen Du, Huayuan Ou, Tinglan Chen, Runsheng Ge, Duan Ma, Jin Zhang

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of cellular and molecular medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.5field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

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  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Meiqin ZhangKey Laboratory of Metabolism and Molecular Medicine, Ministry of Education, Department of Biochemistry and Molecular Biology, School of Basic Medical Sciences, & Institutes of Biomedical Sciences, Shanghai Medical College, Fudan University, Shanghai, China.ORCID 0000-0002-6069-9496
Nan JiangKey Laboratory of Metabolism and Molecular Medicine, Ministry of Education, Department of Biochemistry and Molecular Biology, School of Basic Medical Sciences, & Institutes of Biomedical Sciences, Shanghai Medical College, Fudan University, Shanghai, China.
Renjie CuiKey Laboratory of Metabolism and Molecular Medicine, Ministry of Education, Department of Biochemistry and Molecular Biology, School of Basic Medical Sciences, & Institutes of Biomedical Sciences, Shanghai Medical College, Fudan University, Shanghai, China.
Sichen DuKey Laboratory of Metabolism and Molecular Medicine, Ministry of Education, Department of Biochemistry and Molecular Biology, School of Basic Medical Sciences, & Institutes of Biomedical Sciences, Shanghai Medical College, Fudan University, Shanghai, China.
Huayuan OuKey Laboratory of Metabolism and Molecular Medicine, Ministry of Education, Department of Biochemistry and Molecular Biology, School of Basic Medical Sciences, & Institutes of Biomedical Sciences, Shanghai Medical College, Fudan University, Shanghai, China.
Tinglan ChenZhongshan Hospital, Fudan University, Shanghai, China.
Runsheng GeKey Laboratory of Metabolism and Molecular Medicine, Ministry of Education, Department of Biochemistry and Molecular Biology, School of Basic Medical Sciences, & Institutes of Biomedical Sciences, Shanghai Medical College, Fudan University, Shanghai, China.
Duan MaKey Laboratory of Metabolism and Molecular Medicine, Ministry of Education, Department of Biochemistry and Molecular Biology, School of Basic Medical Sciences, & Institutes of Biomedical Sciences, Shanghai Medical College, Fudan University, Shanghai, China.
Jin ZhangKey Laboratory of Metabolism and Molecular Medicine, Ministry of Education, Department of Biochemistry and Molecular Biology, School of Basic Medical Sciences, & Institutes of Biomedical Sciences, Shanghai Medical College, Fudan University, Shanghai, China.
Shanghai Medical College of Fudan University · CNSun Yat-sen University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Recent studies have demonstrated that aberrant long non-coding RNAs (lncRNAs) expression are suggested to be closely associated with multiple human diseases, lung cancer included. However, the roles of lncRNAs in lung cancer are not well understood. In this study, we used microarrays to investigate the aberrantly expressed lncRNAs in the mouse lung adenocarcinoma with P53 knockout and the Kras

Indexed as

Gene Expression ProfilingGene Expression Regulation, NeoplasticAdenocarcinoma of LungAnimalsBase SequenceCell HypoxiaCell Line, TumorCell MovementCell ProliferationHEK293 CellsHumansLung NeoplasmsMice, KnockoutMutationOncogenesProto-Oncogene Proteins p21(ras)Hras protein, mouseProto-Oncogene Proteins p21(ras)RNA, Long NoncodingTumor Suppressor Protein p53hypoxiaKraslong non-coding RNAsmouse lung adenocarcinomasp53

Identifiers

PMID31410985
PMCPMC6787463
OpenAlexW2967343815

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.