Evidence map›Paper›PMID 31410812›Full record

ArticleJournal of general internal medicine2020

Mild Cognitive Impairment and Receipt of Treatments for Acute Myocardial Infarction in Older Adults.

Deborah A Levine, Kenneth M Langa, Andrzej Galecki, Mohammed Kabeto, Lewis B Morgenstern, Darin B Zahuranec, Bruno Giordani, Lynda D Lisabeth, Brahmajee K Nallamothu

Open access · bronzeAbstract read
In one paragraph

Article in Journal of general internal medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 34 citations in OpenAlex.

  1. Review
  2. Review
  3. Care pathways for patients with cognitive impairment and chronic kidney disease.Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association · 2025
    Review
  4. Article
  5. Article
  6. Article
  7. Role of Cognitive Frailty in Older Adults With Cardiovascular Disease.Journal of the American Heart Association · 2024
    Review
  8. Article
  9. The Association of Cognitive Status and Post-Operative Opioid Prescribing in Older Adults.Annals of surgery open : perspectives of surgical history, education, and clinical approaches · 2023
    Article
  10. Influence of mild cognitive impairment on patient and care partner decision-making for acute ischemic stroke.Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association · 2023
    Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Physician Diagnosis and Knowledge of Mild Cognitive Impairment.Journal of Alzheimer's disease : JAD · 2022
    Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Deborah A LevineDepartment of Internal Medicine, University of Michigan (U-M), North Campus Research Complex, 2800 Plymouth Road, Building 16, Room 430W, Ann Arbor, MI, 48109-2800, USA. deblevin@umich.edu.
Kenneth M LangaDepartment of Internal Medicine, University of Michigan (U-M), North Campus Research Complex, 2800 Plymouth Road, Building 16, Room 430W, Ann Arbor, MI, 48109-2800, USA.
Andrzej GaleckiDepartment of Internal Medicine, University of Michigan (U-M), North Campus Research Complex, 2800 Plymouth Road, Building 16, Room 430W, Ann Arbor, MI, 48109-2800, USA.
Mohammed KabetoDepartment of Internal Medicine, University of Michigan (U-M), North Campus Research Complex, 2800 Plymouth Road, Building 16, Room 430W, Ann Arbor, MI, 48109-2800, USA.
Lewis B MorgensternDepartment of Neurology and Stroke Program, U-M, Ann Arbor, MI, USA.
Darin B ZahuranecDepartment of Neurology and Stroke Program, U-M, Ann Arbor, MI, USA.
Bruno GiordaniDepartment of Psychiatry & Michigan Alzheimer's Disease Center, U-M, Ann Arbor, MI, USA.
Lynda D LisabethDepartment of Neurology and Stroke Program, U-M, Ann Arbor, MI, USA.
Brahmajee K NallamothuDepartment of Internal Medicine, University of Michigan (U-M), North Campus Research Complex, 2800 Plymouth Road, Building 16, Room 430W, Ann Arbor, MI, 48109-2800, USA.
University of Michigan–Ann Arbor · USAnn Arbor Center for Independent Living · USInstitute for Healthcare Improvement · US

Funding

HRS Yrs29-34: Y33 SSA CoFundingU01AG009740 · NIA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Jessica Faul, KENNETH M LANGA · 1990 to 2026
$555.8M
Research Education CoreP30AG024824 · NIA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Neil Alexander · 2004 to 2026
$29.2M
Michigan Alzheimer's Disease Core CenterP30AG053760 · NIA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI LIEBERMAN, ANDREW P · 2016 to 2020
$10.1M
The Effect of Lower Blood Pressure over the Life Course on Late-life Cognition in Blacks, Hispanics, and Whites (BP-COG)R01NS102715 · NINDS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI LEVINE, DEBORAH ALLISON · 2017 to 2021
$3.8M
Decision Making for Cardiovascular Therapy in Adults with Mild Cognitive ImpairmentR01AG051827 · NIA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI LEVINE, DEBORAH ALLISON · 2016 to 2020
$3.6M
NIA NIH HHS P30 AG024824NIA NIH HHS P30 AG053760NIA NIH HHS R01 AG051827NIA NIH HHS U01 AG009740NINDS NIH HHS R01 NS102715
6 · The paper itself

Abstract

backgroundOlder adults with mild cognitive impairment (MCI) should receive evidence-based treatments when indicated. Providers and patients may overestimate the risk of dementia in patients with MCI leading to potential under-treatment. However, the association between pre-existing MCI and receipt of evidence-based treatments is uncertain.

objectiveTo compare receipt of treatments for acute myocardial infarction (AMI) between older adults with pre-existing MCI and cognitively normal patients.

designProspective study using data from the nationally representative Health and Retirement Study, Medicare, and American Hospital Association.

participantsSix hundred nine adults aged 65 or older hospitalized for AMI between 2000 and 2011 and followed through 2012 with pre-existing MCI (defined as modified Telephone Interview for Cognitive Status score of 7-11) and normal cognition (score of 12-27). MAIN MEASURES: Receipt of cardiac catheterization and coronary revascularization within 30 days and cardiac rehabilitation within 1 year of AMI hospitalization. KEY

resultsAmong the survivors of AMI, 19.2% had pre-existing MCI (55.6% were women and 44.4% were male, with a mean [SD] age of 82.3 [7.5] years), and 80.8% had normal cognition (45.7% were women and 54.3% were male, with a mean age of 77.1 [7.1] years). Survivors of AMI with pre-existing MCI were significantly less likely than those with normal cognition to receive cardiac catheterization (50% vs 77%; P < 0.001), coronary revascularization (29% vs 63%; P < 0.001), and cardiac rehabilitation (9% vs 22%; P = 0.001) after AMI. After adjusting for patient and hospital factors, pre-existing MCI remained associated with lower use of cardiac catheterization (adjusted hazard ratio (aHR), 0.65; 95% CI, 0.48-0.89; P = 0.007) and coronary revascularization (aHR, 0.55; 95% CI, 0.37-0.81; P = .003), but not cardiac rehabilitation (aHR, 1.01; 95% CI, 0.49-2.07; P = 0.98).

conclusionsPre-existing MCI is associated with lower use of cardiac catheterization and coronary revascularization but not cardiac rehabilitation after AMI.

Indexed as

Cognitive DysfunctionMyocardial InfarctionAgedChildFemaleHospitalizationHumansMaleMedicareProspective StudiesUnited StatesagingAlzheimer’scardiovascular diseasehealth services research

Identifiers

PMID31410812
PMCPMC6957594
OpenAlexW2967949488

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.