Evidence map›Paper›PMID 31410743›Full record

ArticleClinical journal of gastroenterology2020

Hepatocellular metastasis recurrence in liver transplant after treatment with direct antiviral agents.

Silvia Maier, Debora Donnini, Laura De Luca, Claudio Avellini, Leonardo Alberto Sechi, Giorgio Soardo

Abstract readCase Reports
PubMed Publisher
In one paragraph

Article in Clinical journal of gastroenterology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.1field-weighted citation impact, top 48% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Silvia MaierLiver Unit, Internal Medicine, Department of Medicine (DAME), University School of Medicine of Udine, Piazzale S. M. Misericordia 1, 33100, Udine, Italy.
Debora DonniniLiver Unit, Internal Medicine, Department of Medicine (DAME), University School of Medicine of Udine, Piazzale S. M. Misericordia 1, 33100, Udine, Italy.
Laura De LucaLiver Unit, Internal Medicine, Department of Medicine (DAME), University School of Medicine of Udine, Piazzale S. M. Misericordia 1, 33100, Udine, Italy.
Claudio AvelliniDepartment of Laboratory Medicine, Institute of Pathological Anatomy, University School of Medicine of Udine, Udine, Italy.
Leonardo Alberto SechiLiver Unit, Internal Medicine, Department of Medicine (DAME), University School of Medicine of Udine, Piazzale S. M. Misericordia 1, 33100, Udine, Italy.
Giorgio SoardoLiver Unit, Internal Medicine, Department of Medicine (DAME), University School of Medicine of Udine, Piazzale S. M. Misericordia 1, 33100, Udine, Italy. giorgio.soardo@asuiud.sanita.fvg.it.ORCID http://orcid.org/0000-0003-3181-5651
University of Udine · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chronic HCV liver infection is considered one of the main causes of liver cirrhosis and hepatocellular carcinoma (HCC). For a selected group of patients, orthotopic liver transplantation (OLTx) is the most effective option to cure both liver diseases. After liver transplantation, patients may be at risk of viral infection reactivation and HCC recurrence. HCV recurrence on the transplanted organ can lead to graft cirrhosis and therefore the clearance of virus with antiviral therapies has a pivotal role on the prevention of graft damage. Nowadays, direct antiviral agents (DAAs) represent the choice treatment for HCV recurrence in liver transplanted patients, ensuring high eradication rates. We present the case of a liver transplant recipient who developed, 7 years after OLTx and immediately after a DAAs treatment, a subcutaneous abdominal mass with histological characteristics of HCC.

Indexed as

Liver TransplantationAntiviral AgentsCarcinoma, HepatocellularHepatitis C, ChronicHumansLiver NeoplasmsMaleMiddle AgedNeoplasm Recurrence, LocalPostoperative ComplicationsRecurrenceAntiviral AgentsDirect antiviral agentsHepatitis C infectionHepatocellular carcinoma metastasisOrthotopic liver transplantation

Identifiers

PMID31410743
OpenAlexW2967538626

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.