Evidence map›Paper›PMID 31410738›Full record

ArticleAnnals of intensive care2019

Electrical impedance tomography during spontaneous breathing trials and after extubation in critically ill patients at high risk for extubation failure: a multicenter observational study.

Federico Longhini, Jessica Maugeri, Cristina Andreoni, Chiara Ronco, Andrea Bruni, Eugenio Garofalo, Corrado Pelaia, Camilla Cavicchi, Sergio Pintaudi, Paolo Navalesi

2 registry-linked trialsOpen access · goldAbstract read
In one paragraph

Article in Annals of intensive care, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 30 papers.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed
4.5field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03894332 completednot on this map

Electrical Impedance Tomography During Spontaneous Breathing Trial and Extubation Failure in Critically Ill Patients: an Observational Study

TypeobservationalSponsorUniversity Magna GraeciaRan2015 to 2016Enrolled80ConditionsWeaning Failure, Mechanical Ventilation ComplicationArmsElectrical Impedance Tomography (EIT)
NCT06689020 not yet recruitingnot on this mapstarted 2024, after this paper: background citation

Effect of Continuous High-frequency Oscillation (CHFO) and Continuous Positive Expiratory Pressure (CPEP) Therapy on Lung RECRUITment Using Electrical Impedance Tomography (EIT) - The PEP-RECRUIT Study

TypeobservationalSponsorUniversity of GenovaRan2024 to 2025Enrolled26ConditionsRecruitment, Respiratory FailureArmsContinuous high-frequency oscillation (CHFO) and continuous positive expiratory pressure (CPEP) therapy
3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 63 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 1 country.

Federico LonghiniAnesthesia and Intensive Care, Sant'Andrea Hospital, ASL VC, Vercelli, Italy.
Jessica MaugeriAnesthesia and Intensive Care, "Garibaldi Centro" Hospital, ARNAS Garibaldi, Catania, Italy.
Cristina AndreoniAnesthesia and Intensive Care, Infermi Hospital, AUSL Romagna, Rimini, Italy.
Chiara RoncoAnesthesia and Intensive Care, Sant'Andrea Hospital, ASL VC, Vercelli, Italy.
Andrea BruniAnesthesia and Intensive Care Unit, University Hospital Mater Domini, Department of Medical and Surgical Sciences, Magna Graecia University, Viale Europa - Loc. Germaneto, 88100, Catanzaro, Italy.
Eugenio GarofaloAnesthesia and Intensive Care Unit, University Hospital Mater Domini, Department of Medical and Surgical Sciences, Magna Graecia University, Viale Europa - Loc. Germaneto, 88100, Catanzaro, Italy.
Corrado PelaiaAnesthesia and Intensive Care Unit, University Hospital Mater Domini, Department of Medical and Surgical Sciences, Magna Graecia University, Viale Europa - Loc. Germaneto, 88100, Catanzaro, Italy.
Camilla CavicchiAnesthesia and Intensive Care, Infermi Hospital, AUSL Romagna, Rimini, Italy.
Sergio PintaudiAnesthesia and Intensive Care, "Garibaldi Centro" Hospital, ARNAS Garibaldi, Catania, Italy.
Paolo NavalesiAnesthesia and Intensive Care Unit, University Hospital Mater Domini, Department of Medical and Surgical Sciences, Magna Graecia University, Viale Europa - Loc. Germaneto, 88100, Catanzaro, Italy. pnavalesi@unicz.it.ORCID http://orcid.org/0000-0002-3733-3453
Magna Graecia University · ITCTO Andrea Alesini · ITOspedale Garibaldi · ITOspedale Infermi di Rimini · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThis study aims to assess the changes in lung aeration and ventilation during the first spontaneous breathing trial (SBT) and after extubation in a population of patients at risk of extubation failure.

methodsWe included 78 invasively ventilated patients eligible for their first SBT, conducted with low positive end-expiratory pressure (2 cm H

resultsCompared to SBT success (n = 61), SBT failure (n = 17) showed a greater reduction in ∆EELI at SBT_0 (p < 0.001) and SBT_30 (p = 0.001) and a higher inhomogeneity index at baseline (p = 0.002), SBT_0 (p = 0.003) and SBT_30 (p = 0.005). RR/Vt was not different between groups at baseline but was significantly greater at SBT_0 and SBT_30 in SBT failures, compared to SBT successes (p < 0.001 for both). No differences in ∆Vt% and arterial blood gases were observed between SBT success and failure. The ∆Vt%, ∆EELI, inhomogeneity index and arterial blood gases were not different between patients with extubation success (n = 39) and failure (n = 22) (p > 0.05 for all comparisons).

conclusionsCompared to SBT success, SBT failure was characterized by more lung de-recruitment and inhomogeneity. Whether EIT may be useful to monitor SBT remains to be determined. No significant changes in lung ventilation, aeration or homogeneity related to extubation outcome occurred up to 30 min after extubation. Trial registration Retrospectively registered on clinicaltrials.gov (Identifier: NCT03894332; release date 27th March 2019).

Indexed as

Electrical impedance tomographyExtubation failureMechanical ventilationPost-extubation respiratory failureSpontaneous breathing trialWeaning

Identifiers

PMID31410738
PMCPMC6692788
OpenAlexW2968647901

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.