ArticleJournal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology2021
Diastolic dyssynchrony assessment by gated myocardial perfusion-SPECT in subjects who underwent cardiac resynchronization therapy.
Article in Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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12 citing papers in PubMed.
- Peak filling rate assessed by myocardial perfusion imaging predicts adverse outcomes in women with chronic coronary syndromes.Quantitative imaging in medicine and surgery · 2026Article
- Clinical phenotypes among patients that underwent cardiac resynchronization therapy using unsupervised learning integrating gated SPECT.Nuclear medicine communications · 2025Article
- Novel indices representing heterogeneous distributions of myocardial perfusion imaging.Annals of nuclear medicine · 2024Article
- Left ventricular mechanical dyssynchrony in patients with heart failure: What is the next step?Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2022Article
- Incremental value of left ventricular shape parameters measured by gated SPECT MPI in predicting the super-response to CRT.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2022Article
- Gated SPECT left ventricular shape and prediction of super responders to cardiac resynchronization therapy: Not so easy as it (LV) looks.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2022Article
- Left ventricular systolic and diastolic dyssynchrony to improve cardiac resynchronization therapy response in heart failure patients with dilated cardiomyopathy.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2021Article
- Technical aspects of gated SPECT MPI assessment of left ventricular dyssynchrony used in the VISION-CRT study.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2021Article
- Parameters of left ventricular systolic and diastolic dyssynchrony on radionuclide imaging to improve cardiac resynchronization therapy in heart failure patients with dilated cardiomyopathy.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2021Article
- Intraventricular synchronism assessment by gated-SPECT myocardial perfusion imaging in cardiac resynchronization therapy. Does cardiomyopathy type influence results?EJNMMI research · 2020Article
- Dyssynchrony as a marker of adverse prognosis among patients with coronary artery disease and heart failure.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2020Article
- Impact of International Atomic Energy Agency support to the development of nuclear cardiology in low-and-middle-income countries: Case of Latin America and the Caribbean.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2019Article
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18 authors.
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Abstract
backgroundLeft ventricular diastolic dyssynchrony (LVDD) can be assessed by gated myocardial perfusion single-photon emission computed tomography (GMP-SPECT). LVDD is an area of interest in subjects who underwent cardiac resynchronization therapy (CRT). The aim of this post hoc analysis was to assess the role of LVDD in subjects with CRT who were followed up at 6-month period. MATERIAL &
methodsLeft ventricular diastolic dyssynchrony was assessed by GMP-SPECT at baseline and after CRT procedure in 160 subjects from 10 different cardiological centers. CRT procedure was performed as per current guidelines. Outcomes were defined as improvement in ≥1 New York Heart Association (NYHA) class, left ventricular ejection fraction (LVEF) by 5%, and reduction in end-systolic volume (ESV) by 15% and 5% points in Minnesota Living with Heart Failure Questionnaire. LVDD was defined as diastolic phase standard deviation ≥40 ± 14°.
resultsImprovement in NYHA functional class occurred in 105 (65.6%), LVEF in 74 (46.3%), decrease in ESV in 86 (53.8%), and Minnesota score in 85 (53.1%) cases. Baseline LV diastolic standard deviation was 53.53° ± 20.85 and at follow-up 40.44° ± 26.1283; (P < 0.001). LVDD was not associated with improvement in clinical outcomes at follow-up.
conclusionCRT improves both systolic and diastolic dyssynchrony values at 6-month follow-up. LVDD at baseline is correlated with cardiac functionality at follow-up, but not with overall favorable clinical outcomes.
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