Evidence map›Paper›PMID 31410643›Full record

ArticleCardiovascular toxicology2020

Vehicular Particulate Matter (PM) Characteristics Impact Vascular Outcomes Following Inhalation.

Katherine E Zychowski, Christina R Steadman Tyler, Bethany Sanchez, Molly Harmon, June Liu, Hammad Irshad, Jacob D McDonald, Barry E Bleske, Matthew J Campen

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cardiovascular toxicology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.7field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 9 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Katherine E ZychowskiDepartment of Pharmaceutical Sciences, The University of New Mexico, College of Pharmacy, Albuquerque, NM, USA. KZychowski@salud.unm.edu.
Christina R Steadman TylerBiosciences Division, Los Alamos National Laboratories, Los Alamos, NM, USA.
Bethany SanchezDepartment of Pharmaceutical Sciences, The University of New Mexico, College of Pharmacy, Albuquerque, NM, USA.
Molly HarmonDepartment of Pharmaceutical Sciences, The University of New Mexico, College of Pharmacy, Albuquerque, NM, USA.
June LiuLovelace Respiratory Research Institute, Albuquerque, NM, USA.
Hammad IrshadLovelace Respiratory Research Institute, Albuquerque, NM, USA.
Jacob D McDonaldLovelace Respiratory Research Institute, Albuquerque, NM, USA.
Barry E BleskeDepartment of Pharmacy Practice & Administrative Sciences, The University of New Mexico, College of Pharmacy, Albuquerque, NM, USA.
Matthew J CampenDepartment of Pharmaceutical Sciences, The University of New Mexico, College of Pharmacy, Albuquerque, NM, USA.
University of New Mexico · USLovelace Respiratory Research Institute · USLos Alamos National Laboratory · US

Funding

FAIR Data Competency and Machine Learning Readiness for Biomedical ScientistsK12GM088021 · NIGMS · UNIVERSITY OF NEW MEXICO HEALTH SCIS CTR · PI REBECCA S. HARTLEY, Diane Lidke · 2009 to 2026
$16.4M
Mechanisms of Vascular Toxicity from Inhaled ToxicantsR01ES014639 · NIEHS · UNIVERSITY OF NEW MEXICO HEALTH SCIS CTR · PI CAMPEN, MATTHEW J · 2008 to 2023
$6.7M
Neurovascular Consequences of Inhaled Uranium Mine-Site Dust ExposureR00ES029104 · NIEHS · UNIVERSITY OF NEW MEXICO HEALTH SCIS CTR · PI ZYCHOWSKI, KATHERINE · 2020 to 2022
$743k
Neurovascular Consequences of Inhaled Uranium Mine-Site Dust ExposureK99ES029104 · NIEHS · UNIVERSITY OF NEW MEXICO HEALTH SCIS CTR · PI ZYCHOWSKI, KATHERINE · 2018 to 2019
$172k
Enhancement of Coronary Constriction by Volatile Organic Air ToxicsR56ES014639 · NIEHS · UNIVERSITY OF NEW MEXICO HEALTH SCIS CTR · PI CAMPEN, MATTHEW J · 2013 to 2013
$148k
NIEHS NIH HHS K99 ES029104NIEHS NIH HHS R00 ES029104NIEHS NIH HHS R01 ES014639NIEHS NIH HHS R56 ES014639NIGMS NIH HHS K12 GM088021
6 · The paper itself

Abstract

Roadside proximity and exposure to mixed vehicular emissions (MVE) have been linked to adverse pulmonary and vascular outcomes. However, because of the complex nature of the contribution of particulate matter (PM) versus gases, it is difficult to decipher the precise causative factors regarding PM and the copollutant gaseous fraction. To this end, C57BL/6 and apolipoprotein E knockout mice (ApoE

Indexed as

AnimalsAortaAortic DiseasesAtherosclerosisChemokine CCL2Chemokine CCL5Chemokine CXCL1Disease Models, AnimalEndothelin-1Inhalation ExposureMaleMice, Inbred C57BLMice, Knockout, ApoEParticulate MatterRisk AssessmentTumor Necrosis Factor-alphaCcl2 protein, mouseCcl5 protein, mouseChemokine CCL2Chemokine CCL5Chemokine CXCL1Cxcl1 protein, mouseEndothelin-1Particulate MatterTnf protein, mouseTumor Necrosis Factor-alphaVehicle EmissionsCardiovascularDiesel exhaustParticulate matterPulmonaryVascular toxicityVehicle emissions

Identifiers

PMID31410643
PMCPMC7015791
OpenAlexW2967811763

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.