Evidence map›Paper›PMID 31410624›Full record

ArticleEuropean radiology experimental2019

Bone strain index reproducibility and soft tissue thickness influence: a dual x-ray photon absorptiometry phantom study.

C Messina, L P Piodi, L Rinaudo, I Emili, F Porro, C Buonomenna, L M Sconfienza, L Vergani, F M Ulivieri

Abstract read
In one paragraph

Article in European radiology experimental, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Article
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  10. Review
  11. Comparison of Differences in Bone Mineral Density Measurement With 3 Hologic Dual-Energy X-Ray Absorptiometry Scan Modes.Journal of clinical densitometry : the official journal of the International Society for Clinical Densitometry
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

C MessinaIRCCS Istituto Ortopedico Galeazzi, Via Riccardo Galeazzi 4, 20161, Milano, Italy.
L P PiodiFormer: Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Gastroenterology and Digestive Endoscopy Unit, Via Francesco Sforza 35, 20122, Milano, Italy.
L RinaudoTECHNOLOGIC Srl, Lungo Dora Voghera 34/36A, 10153, Torino, Italy.
I EmiliPostgraduate School of Radiodiagnostic, University of Milan, Via Festa del Perdono 7, 20122, Milano, Italy.
F PorroPostgraduate School of Physical Medicine and Rehabilitation Therapy, University of Milan, Via Festa del Perdono 7, 20122, Milano, Italy.
C BuonomennaPostgraduate School of Radiodiagnostic, University of Milan, Via Festa del Perdono 7, 20122, Milano, Italy.
L M SconfienzaIRCCS Istituto Ortopedico Galeazzi, Via Riccardo Galeazzi 4, 20161, Milano, Italy.
L VerganiDepartment of Mechanical Engineering Politecnico di Milano, Via Giuseppe La Masa 1, 20156, Milano, Italy.
F M UlivieriFondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Nuclear Medicine, Bone Metabolic Unit, Via Francesco Sforza 35, 20122, Milano, Italy. ulivieri@gmail.com.ORCID 0000-0003-1357-3425

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundBone strain index (BSI) is a tool measuring bone strain, derived from dual x-ray photon absorptiometry. It is able to characterise an aspect of bone quality that, joined to the quantity and quality parameters of bone mineral density (BMD) and trabecular bone score (TBS), permits an accurate definition of fracture risk. As no data are available about BSI precision, our aim was to assess its in vitro reproducibility.

methodsA Hologic spine phantom was used to perform BSI scans with three different scan modes: fast array (FA), array (A), and high definition (HD). Different soft tissue thicknesses (1, 3, 6 cm) of fresh pork rind layers as a surrogate of abdominal fat were interposed. For each scan mode, the phantom was consecutively scanned 25 times without repositioning.

resultsIn all scan modes (FA, A, HD) and at every fat thickness, BSI reproducibility was lower than that of BMD. The highest reproducibility was found using HD-mode with 1 cm of pork rind and the lowest one using HD-mode with 6 cm of pork rind. Increasing fat thickness, BSI reproducibility tended to decrease. BSI least significant change appeared to be about three times that of BMD in all modalities and fat thicknesses. Without pork rind superimposition and with 1-cm fat layer, BSI reproducibility was highest with HD-mode; with 3 or 6 cm fat thickness, it was higher with A-mode.

conclusionsBSI reproducibility was worse than that of BMD, but it is less sensitive to fat thickness increase, similarly to TBS.

Indexed as

Phantoms, ImagingAbdominal FatAbsorptiometry, PhotonAnimalsBone and BonesBone DensityCancellous BoneOrgan SizeReproducibility of ResultsSwineAbsorptiometry (photon)Bone densityBone strain indexFractures (bone)Reproducibility of results

Identifiers

PMID31410624
PMCPMC6692807

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.