Evidence map›Paper›PMID 31410617›Full record

ArticleMikrochimica acta2019

Gold nanoparticle-based detection of dopamine based on fluorescence resonance energy transfer between a 4-(4-dialkylaminostyryl)pyridinium derived fluorophore and citrate-capped gold nanoparticles.

Juanjuan Peng, Na Zhou, Yang Zhong, Yaoquan Su, Lingzhi Zhao, Young-Tae Chang

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In one paragraph

Article in Mikrochimica acta, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.8field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 19 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Juanjuan PengState Key Laboratory of Natural Medicines, School of Basic Medical Sciences and Clinical Pharmacy, China Pharmaceutical University, Nanjing, 211198, Jiangsu, China. pjj@cpu.edu.cn.
Na ZhouSchool of Materials Science and Engineering, Hebei Provincial Key Laboratory of Traffic Engineering Materials, Shijiazhuang Tiedao University, Shijiazhuang, 050043, China.
Yang ZhongState Key Laboratory of Natural Medicines, School of Basic Medical Sciences and Clinical Pharmacy, China Pharmaceutical University, Nanjing, 211198, Jiangsu, China.
Yaoquan SuState Key Laboratory of Natural Medicines, School of Basic Medical Sciences and Clinical Pharmacy, China Pharmaceutical University, Nanjing, 211198, Jiangsu, China.
Lingzhi ZhaoState Key Laboratory of Natural Medicines, School of Basic Medical Sciences and Clinical Pharmacy, China Pharmaceutical University, Nanjing, 211198, Jiangsu, China. zlz@cpu.edu.cn.
Young-Tae ChangCenter for Self-assembly and Complexity, Institute for Basic Science (IBS), Pohang, 37673, South Korea. ytchang@postech.ac.kr.
China Pharmaceutical University · CNInstitute for Basic Science · KRShijiazhuang Tiedao University · CN

Funding

National Natural Science Foundation of China 81701766National Natural Science Foundation of China 81702998
6 · The paper itself

Abstract

A colorimetric/fluorometric dual-signal assay is described for the determination of dopamine (DA). A nanoprobe was obtained by linking a 4-(4-dialkylaminostyryl)pyridinium derived fluorophore to citrate-capped gold nanoparticles (AuNPs). The fluorescence of the fluorophore is quenched by the AuNPs via fluorescence resonance energy transfe. In the presence of DA, the catechol group of DA can absorb on the surface of AuNPs to induce aggregation, which is accompanied by a color change from red to blue. The yellow fluorescence of the fluorophore with excitation/emission maximum at 365/570 nm is recovered. The dual-signal detection allows the quantitative analysis of DA within 300 μM by the colorimetric method and 80 μM by the fluorometric method. The detection limits for the colorimetric/fluorometric methods are 1.85 μM and 0.29 μM, respectively. Quantitative determination of DA in spiked urine samples was successfully demonstrated, with recoveries ranging from 98.2 to 106.0%. Graphical abstract A colorimetric/fluorometric dual-signal assay is described for the determination of dopamine by linking a fluorophore to gold nanoparticles. The dopamine causes aggregation of the nanoparticles to induce color change, which is followed by the recovery of the fluorescence.

Indexed as

Fluorescence Resonance Energy TransferCitric AcidColorColorimetryDopamineFluorescent DyesGoldMetal NanoparticlesPyridinesCitric AcidDopamineFluorescent DyesGoldPyridinesColorimetryDual-signal probeFluorometryTurn-onUrine samples

Identifiers

PMID31410617
OpenAlexW2968662920

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.