Evidence map›Paper›PMID 31410614›Full record

ArticleJournal of the Association for Research in Otolaryngology : JARO2019

Sound Localization in Preweanling Mice Was More Severely Affected by Deleting the Kcna1 Gene Compared to Deleting Kcna2, and a Curious Inverted-U Course of Development That Appeared to Exceed Adult Performance Was Observed in All Groups.

James R Ison, Paul D Allen, Bruce L Tempel, Helen M Brew

Open access · greenAbstract readComparative Study
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of the Association for Research in Otolaryngology : JARO, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact, top 92% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

James R IsonDepartment of Brain and Cognitive Sciences, Meliora Hall, University of Rochester, Rochester, NY, 14627, USA. JIson@ur.rochester.edu.ORCID 0000-0001-6267-5220
Paul D AllenDepartment of Otolaryngology, University of Rochester Medical Center, Rochester, NY, 14642, USA.
Bruce L TempelThe Virginia Merrill Bloedel Hearing Research Center and the Departments of Otolaryngology-Head and Neck Surgery and Pharmacology, University of Washington School of Medicine, Seattle, WA, 98195, USA.
Helen M BrewThe Virginia Merrill Bloedel Hearing Research Center and the Departments of Otolaryngology-Head and Neck Surgery and Pharmacology, University of Washington School of Medicine, Seattle, WA, 98195, USA.
University of Rochester Medical Center · USUniversity of Washington · US

Funding

Structure and Function Services CoreP01AG009524 · NIA · UNIVERSITY OF SOUTH FLORIDA · PI FRISINA, ROBERT D · 1992 to 2021
$23.2M
UNIVERSITY OF WASHINGTON RESEARCH CORE CENTERP30DC004661 · NIDCD · UNIVERSITY OF WASHINGTON · PI RAIBLE, DAVID W, STONE, JENNIFER S. · 2000 to 2014
$11.1M
Technology and Comp CoreP30DC005409 · NIDCD · UNIVERSITY OF ROCHESTER · PI PAIGE, GARY D · 2002 to 2012
$4.3M
GENETIC MODEL FOR CONGENITAL DEAFNESSR01DC002739 · NIDCD · UNIVERSITY OF WASHINGTON · PI TEMPEL, BRUCE L · 1995 to 2013
$4.1M
NIA NIH HHS P01 AG009524NIDCD NIH HHS P30 DC004661NIDCD NIH HHS P30 DC005409NIDCD NIH HHS R01 DC002739
6 · The paper itself

Abstract

The submillisecond acuity for detecting rapid spatial and temporal fluctuations in acoustic stimuli observed in humans and laboratory animals depends in part on select groups of auditory neurons that preserve synchrony from the ears to the binaural nuclei in the brainstem. These fibers have specialized synapses and axons that use a low-threshold voltage-activated outward current, I

Indexed as

Sound LocalizationAcoustic StimulationAnimalsFemaleKv1.1 Potassium ChannelKv1.2 Potassium ChannelMaleMiceMice, Inbred C3HMotor ActivityNoiseReflex, StartleWeaningKcna1 protein, mouseKcna2 protein, mouseKv1.1 Potassium ChannelKv1.2 Potassium Channelacoustic startle reflexDeletion Kv1 subunitsnoise offsetsound localization

Identifiers

PMID31410614
PMCPMC6889093
OpenAlexW2967405248

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.