Evidence map›Paper›PMID 31410598›Full record

Trial reportSupportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer2020

Exploratory analyses of the Danish Palliative Care Trial (DanPaCT): a randomized trial of early specialized palliative care plus standard care versus standard care in advanced cancer patients.

Anna Thit Johnsen, Morten Aagaard Petersen, Per Sjøgren, Lise Pedersen, Mette Asbjoern Neergaard, Anette Damkier, Christian Gluud, Peter Fayers, Jane Lindschou, Annette S Strömgren and 3 more

Registry-linked trialAbstract readMulticenter StudyRandomized Controlled Trial
PubMed Publisher
In one paragraph

Trial report in Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01348048 (Danish Palliative Care Trial), which is not on this map. Cited by 16 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01348048 phase4completednot on this map

Danish Palliative Care Trial (DanPaCT): A Randomised Clinical Multi-centre Trial Investigating the Effect of Specialised Palliative Care on Symptoms, Survival, Economical Factors and Satisfaction in Patients With Cancer Reporting Palliative Needs

TypeinterventionalSponsorBispebjerg HospitalRan2011 to 2014Enrolled306ConditionsMetastatic CancerArmsSpecialised palliative care (SPC)
3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
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  7. Review
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  11. Palliative Care in the Ageing European Population: A Cross-Country Comparison.International journal of environmental research and public health · 2024
    Article
  12. The quality of end of life care for Danish cancer patients who have received specialized palliative: a national survey using the Danish version of VOICES-SF.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2022
    Article
  13. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Anna Thit JohnsenThe Research Unit, Department of Palliative Medicine, Bispebjerg Hospital, Copenhagen University Hospital, Copenhagen, Denmark. atjohnsen@health.sdu.dk.ORCID http://orcid.org/0000-0003-0753-9634
Morten Aagaard PetersenThe Research Unit, Department of Palliative Medicine, Bispebjerg Hospital, Copenhagen University Hospital, Copenhagen, Denmark.
Per SjøgrenDepartment of Oncology, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark.
Lise PedersenThe Research Unit, Department of Palliative Medicine, Bispebjerg Hospital, Copenhagen University Hospital, Copenhagen, Denmark.
Mette Asbjoern NeergaardPalliative Care Team, Department of Oncology, Aarhus University Hospital, Aarhus, Denmark.
Anette DamkierPalliative Team Fyn, Odense University Hospital, Odense, Denmark.
Christian GluudThe Copenhagen Trial Unit, Centre for Clinical Intervention Research, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark.
Peter FayersInstitute of Applied Health Sciences, University of Aberdeen Medical School, Aberdeen, Scotland, UK.
Jane LindschouThe Copenhagen Trial Unit, Centre for Clinical Intervention Research, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark.
Annette S StrömgrenThe Research Unit, Department of Palliative Medicine, Bispebjerg Hospital, Copenhagen University Hospital, Copenhagen, Denmark.
Jan Bjoern NielsenPalliative Team Herning, Herning Hospital, Herning, Denmark.
Irene J HigginsonKing's College London, Cicely Saunders Institute, Department of Palliative Care, Policy and Rehabilitation, London, UK.
Mogens GroenvoldThe Research Unit, Department of Palliative Medicine, Bispebjerg Hospital, Copenhagen University Hospital, Copenhagen, Denmark.

Funding

Kræftens Bekæmpelse R16-A695 and R114-A7232-14-S3TrygFonden 7-10-0838A and 7-12-0754
6 · The paper itself

Abstract

backgroundEarly and integrated specialized palliative care is often recommended but has still only been investigated in relatively few randomized clinical trials.

objectiveTo investigate the effect of early specialized palliative care plus standard care versus standard care on the explorative outcomes in the Danish Palliative Care Trial (DanPaCT).

methodsWe conducted a randomized multicentre, parallel-group clinical trial. Consecutive patients with metastatic cancer were included if they had symptoms or problems that exceeded a predefined threshold according to the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire (EORTC QLQ-C30). Outcomes were estimated as the differences between the intervention and the control groups in the change from baseline to the weighted mean of the 3- and 8-week follow-ups measured as areas under the curve.

resultsIn total, 145 patients were randomized to early specialized palliative care plus standard care versus 152 to standard care only. Early specialized palliative care had no significant effect on any of the symptoms or problems. Of the 21 items addressing satisfaction, specialized palliative care improved the item 'overall satisfaction with the help received from the health care system' with 9 points (95% confidence interval 3.8 to 14.2, p = 0.0006) and three other items (all p < 0.05).

conclusionIn line with the analyses of the primary and secondary outcomes in DanPaCT, we did not find that specialized palliative care, as provided in DanPaCT, affected symptoms and problems. However, patients in the intervention group seemed more satisfied with the health care received than those in the standard care group.

trial registrationNCT01348048.

Indexed as

AgedAged, 80 and overDenmarkFemaleHospice and Palliative Care NursingHumansMaleMiddle AgedNeoplasmsPalliative CarePatient SatisfactionQuality of LifeSurveys and QuestionnairesDepressionNeoplasmsPalliative carePatient satisfactionQuality of lifeRandomized clinical trial

Identifiers

PMID31410598

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.