Evidence map›Paper›PMID 31410576›Full record

ArticleMikrochimica acta2019

Electrochemical determination of Salmonella typhimurium by using aptamer-loaded gold nanoparticles and a composite prepared from a metal-organic framework (type UiO-67) and graphene.

Ge Dai, Zhi Li, Feifei Luo, Shiyun Ai, Bo Chen, Qingjiang Wang

Abstract read
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In one paragraph

Article in Mikrochimica acta, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed.

  1. Zirconium-based metal-organic frameworks for pathogen detection.Analytical sciences : the international journal of the Japan Society for Analytical Chemistry · 2026
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  7. Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Advancement inBiosensors · 2021
    Review
  13. Review
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  15. Aptamer-based approaches for the detection of waterborne pathogens.International microbiology : the official journal of the Spanish Society for Microbiology · 2021
    Review
  16. Article
  17. Article
  18. Review
  19. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Ge DaiSchool of Chemistry and Molecular Engineering, East China Normal University, 500 Dongchuan Road, Shanghai, 200241, People's Republic of China.
Zhi LiSchool of Chemistry and Molecular Engineering, East China Normal University, 500 Dongchuan Road, Shanghai, 200241, People's Republic of China.
Feifei LuoSchool of Chemistry and Molecular Engineering, East China Normal University, 500 Dongchuan Road, Shanghai, 200241, People's Republic of China.
Shiyun AiCollege of Chemistry and Material Science, Shandong Agricultural University, Taian, 271018, Shandong, People's Republic of China.
Bo ChenSchool of Chemistry and Molecular Engineering, East China Normal University, 500 Dongchuan Road, Shanghai, 200241, People's Republic of China. bchen@chem.ecnu.edu.cn.
Qingjiang WangSchool of Chemistry and Molecular Engineering, East China Normal University, 500 Dongchuan Road, Shanghai, 200241, People's Republic of China. qjwang@chem.ecnu.edu.cn.

Funding

National Natural Science Foundation of China No. 21575042
6 · The paper itself

Abstract

An aptamer based assay is described for the determination of Salmonella typhimurium (S.typhimurium). A metal-organic framework-graphene composite of type UiO-67/GR is used as the substrate, and an aptamer-gold nanoparticles-horseradish peroxidase (Apt-AuNP-HRP) conjugate the signal amplification probe. A phosphate-terminal and partially complementary DNA (cDNA) of the aptamer is covalently bound to UiO-67/GR via the chemical complexation between phosphate and Zr-OH groups of UiO-67, and then S. typhimurium and cDNA will compete for the binding sites. The binding of Apt-AuNP-HRP to S.typhimurium leads to the formation of strong conjugates. The unbound signal probes then attach to the surface of a glassy carbon electrode via hybridization with cDNA. This generates a large current response (best measured at a potential as low as -0.02 V vs. saturated calomel electrode) under the catalytic action of HRP on the H

Indexed as

AnimalsAptamers, NucleotideBase SequenceBiosensing TechniquesElectrochemistryGoldGraphiteMetal NanoparticlesMetal-Organic FrameworksMilkSalmonella typhimuriumAptamers, NucleotideGoldGraphiteMetal-Organic FrameworksCompetitiveCyclic voltammetryDifferential pulse voltammetryElectrochemical impedance spectroscopyFoodborne pathogensHorseradish peroxidaseIn-situ synthesisMilkSignal-offZr-MOF

Identifiers

PMID31410576

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.