Evidence map›Paper›PMID 31410222›Full record

ArticleTheranostics2019

RNA-silencing nanoprobes for effective activation and dynamic imaging of neural stem cell differentiation.

Ruili Zhang, Zhe Wang, Zuo Yang, Linlin Wang, Zhongdi Wang, Baihang Chen, Zhongliang Wang, Jie Tian

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Theranostics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Review
  3. Recent Advances in Stimulus-Responsive Nanocarriers for Gene Therapy.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2021
    Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Ruili ZhangEngineering Research Center of Molecular- and Neuro-imaging of ministry of education, School of Life Science and Technology, Xidian University, Xi'an, Shaanxi, 710126 China.
Zhe WangLaboratory of Molecular Imaging and Nanomedicine, National Institute of Biomedical Imaging and Bioengineering, National Institutes of Health, Bethesda, Maryland, 20892 USA.
Zuo YangEngineering Research Center of Molecular- and Neuro-imaging of ministry of education, School of Life Science and Technology, Xidian University, Xi'an, Shaanxi, 710126 China.
Linlin WangEngineering Research Center of Molecular- and Neuro-imaging of ministry of education, School of Life Science and Technology, Xidian University, Xi'an, Shaanxi, 710126 China.
Zhongdi WangEngineering Research Center of Molecular- and Neuro-imaging of ministry of education, School of Life Science and Technology, Xidian University, Xi'an, Shaanxi, 710126 China.
Baihang ChenEngineering Research Center of Molecular- and Neuro-imaging of ministry of education, School of Life Science and Technology, Xidian University, Xi'an, Shaanxi, 710126 China.
Zhongliang WangEngineering Research Center of Molecular- and Neuro-imaging of ministry of education, School of Life Science and Technology, Xidian University, Xi'an, Shaanxi, 710126 China.
Jie TianEngineering Research Center of Molecular- and Neuro-imaging of ministry of education, School of Life Science and Technology, Xidian University, Xi'an, Shaanxi, 710126 China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

To achieve the clinical potential of neural stem cells (NSCs), it is crucial to activate NSC differentiation into neurons and simultaneously monitor the process of NSC differentiation. However, there are many challenges associated with regulating and tracking NSC differentiation.

Indexed as

Cell DifferentiationImaging, Three-DimensionalRNA InterferenceAnimalsCell DeathDelayed-Action PreparationsGlutathioneGoldHumansMetal NanoparticlesNeural Stem CellsRNA, MessengerSOX9 Transcription FactorDelayed-Action PreparationsGlutathioneGoldRNA, MessengerSOX9 Transcription Factordrug deliverygene silencinggold nanoparticleimagingneural stem cell

Identifiers

PMID31410222
PMCPMC6691577

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.