Evidence map›Paper›PMID 31410190›Full record

ArticleTheranostics2019

Modulation of Respiration and Mitochondrial Dynamics by SMAC-Mimetics for Combination Therapy in Chemoresistant Cancer.

Judith Hagenbuchner, Herbert Oberacher, Kathrin Arnhard, Ursula Kiechl-Kohlendorfer, Michael J Ausserlechner

Open access · goldAbstract read
In one paragraph

Article in Theranostics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
2.7field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 28 citations in OpenAlex.

  1. Review
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  5. Pepsin enhances glycolysis to promote malignant transformation of vocal fold leukoplakia epithelial cells with dysplasia.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Judith HagenbuchnerDepartment of Pediatrics II, Medical University Innsbruck, Innsbruck, Austria.
Herbert OberacherInstitute of Legal Medicine and Core Facility Metabolomics, Medical University Innsbruck, Innsbruck, Austria.
Kathrin ArnhardInstitute of Legal Medicine and Core Facility Metabolomics, Medical University Innsbruck, Innsbruck, Austria.
Ursula Kiechl-KohlendorferDepartment of Pediatrics II, Medical University Innsbruck, Innsbruck, Austria.
Michael J AusserlechnerDepartment of Pediatrics I, Medical University Innsbruck, Innsbruck, Austria.
Innsbruck Medical University · AT

Funding

Austrian Science Fund FWF I 3089
6 · The paper itself

Abstract

Inhibitor of apoptosis proteins (IAP) are cell death regulators that bind caspases and interfere with apoptotic signalling

Indexed as

AnimalsAntineoplastic AgentsAntineoplastic Combined Chemotherapy ProtocolsApoptosis Regulatory ProteinsBrain NeoplasmsCell Line, TumorCell RespirationDipeptidesDrug Resistance, NeoplasmHEK293 CellsHumansIndolesMiceMice, Inbred BALB CMice, NudeMitochondrial DynamicsAntineoplastic AgentsApoptosis Regulatory ProteinsBIRC5 protein, humanbirinapantDIABLO protein, humanDipeptidesIndolesLCL161Mitochondrial ProteinsSurvivinThiazolesXIAP protein, humanX-Linked Inhibitor of Apoptosis ProteinBIRC4/XIAPBIRC5/survivinSMAC-mimeticsWarburg

Identifiers

PMID31410190
PMCPMC6691393
OpenAlexW2963760980

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.