ArticleExperimental and therapeutic medicine2019
Berberine exhibits antioxidative effects and reduces apoptosis of the vaginal epithelium in bacterial vaginosis.
Article in Experimental and therapeutic medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed, 27 citations in OpenAlex.
- Research Progress in the Treatment of Vaginitis With Bioactive Compounds: Targeting of Vaginal Microflora.MicrobiologyOpen · 2026Review
- Association Between Red Cell Distribution Width-Coefficient of Variation (RDW-CV) and Bacterial Vaginosis: A Cross-Sectional Study and External Validation.International journal of women's health · 2026Article
- Synergistic effects of berberine and adipose stem cells in a silk fibroin-PEG hydrogel for diabetic wound healing via macrophage polarization modulation.Regenerative biomaterials · 2026Article
- Harnessing dual-channel probiotics to synergistically correct intestinal and vaginal dysbiosis after antibiotic disruption.NPJ biofilms and microbiomes · 2025Article
- Hallmarks of Bacterial Vaginosis.Diagnostics (Basel, Switzerland) · 2025Review
- Association between serum carotenoids and bacterial vaginosis infection among American women.BMC infectious diseases · 2024Article
- A non-antibiotic antimicrobial drug, a biological bacteriostatic agent, is useful for treating aerobic vaginitis, bacterial vaginosis, and vulvovaginal candidiasis.Frontiers in microbiology · 2024Article
- Bacterial vaginosis: a review of approaches to treatment and prevention.Frontiers in reproductive health · 2023Review
- Is there any association between adherence to the Mediterranean Diet and Dietary Total Antioxidant Capacity with Bacterial Vaginosis? Results from a Case-Control study.BMC women's health · 2022Article
- Evaluation of the Cytotoxic Activity and Anti-Migratory Effect of Berberine-Phytantriol Liquid Crystalline Nanoparticle Formulation on Non-Small-Cell Lung Cancer In Vitro.Pharmaceutics · 2022Article
- Considerations for Choosing Soluble Immune Markers to Determine Safety of Novel Vaginal Products.Frontiers in reproductive health · 2022Review
- The Antibiofilm Role of Biotics Family in Vaginal Fungal Infections.Frontiers in microbiology · 2022Review
- Evaluation of Berberine as an Adjunct to TB Treatment.Frontiers in immunology · 2021Article
- Dose-dependent beneficial and harmful effects of berberine on mouse oocyte maturation and fertilization and fetal development.Toxicology research · 2020Article
- Apoptosis of vaginal epithelial cells in clinical samples from women with diagnosed bacterial vaginosis.Scientific reports · 2020Observational
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Bacterial vaginosis (BV) is a common type of vaginitis. Berberine is a natural alkaline product that reduces oxidative stress and apoptosis in cells. The aim of the present study was to investigate the effects of berberine on oxidative stress and apoptotic rates of BV. Vaginal epithelial and discharge samples were obtained from 60 healthy individuals and 180 patients with BV before and after one month of berberine treatment. Clinical observation was documented for all patients before and after treatment for comparison. Additionally, an
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Registered trials
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