ArticleExperimental and therapeutic medicine2019
Clinical significance of neutrophil to lymphocyte ratio and platelet to lymphocyte ratio in acute cerebral hemorrhage with gastrointestinal hemorrhage, and logistic regression analysis of risk factors.
Article in Experimental and therapeutic medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed, 22 citations in OpenAlex.
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- Clinical value of inflammatory indices in predicting poor prognosis and post-hemorrhagic hydrocephalus in patients with intraventricular hemorrhage.BMC neurology · 2025Article
- To develop a machine learning-based model for predicting the risk of gastrointestinal bleeding in patients with spontaneous intracerebral hemorrhage.Frontiers in neurology · 2025Article
- Article
- The Clinical Value of Neutrophil-to-Lymphocyte Ratio and Platelet-to-Lymphocyte Ratio for Predicting Hematoma Expansion and Poor Outcomes in Patients with Acute Intracerebral Hemorrhage.Journal of clinical medicine · 2023Article
- Age-to-Glasgow Coma Scale score ratio predicts gastrointestinal bleeding in patients with primary intracerebral hemorrhage.Frontiers in neurology · 2023Article
- Association between platelet-lymphocyte ratio and 90-day mortality in patients with intracerebral hemorrhage: data from the MIMIC-III database.Frontiers in neurology · 2023Article
- Neutrophil-to-Lymphocyte ratio on admission predicts gastrointestinal bleeding in acute basal ganglia hemorrhage.Journal of clinical laboratory analysis · 2022Article
- Emergency department point-of-care biomarkers and day 90 functional outcome in spontaneous intracerebral hemorrhage: A single-center pilot study.Experimental and therapeutic medicine · 2022Article
- The clinical value of neutrophil-to-lymphocyte ratio, platelet-to-lymphocyte ratio, and D-dimer-to-fibrinogen ratio for predicting pneumonia and poor outcomes in patients with acute intracerebral hemorrhage.Frontiers in immunology · 2022Article
- Utility of preoperative systemic inflammatory biomarkers in predicting postoperative complications after pancreaticoduodenectomy: Literature review and single center experience.World journal of gastrointestinal surgery · 2021Article
- Immature Granulocyte Count and Percentage as New Predictors of Mortality in Patients with Upper Gastrointestinal Bleeding.Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine · 2020Article
- miR-7-5p Affects Brain Edema After Intracerebral Hemorrhage and Its Possible Mechanism.Frontiers in cell and developmental biology · 2020Article
- Article
- Is it possible to predict post-adenotonsillectomy hemorrhage in children with preoperative blood tests? Single-center retrospective study.Science progressObservational
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The aim of the present study was to determine the predictive value of the neutrophil to lymphocyte ratio (NLR) and platelet to lymphocyte ratio (PLR) in patients with acute cerebral hemorrhage with or without gastrointestinal hemorrhage. Risk factors of gastrointestinal hemorrhage in patients with acute cerebral hemorrhage were also assessed. A total of 335 patients with acute cerebral hemorrhage admitted to our hospital between January 2012 and January 2017 were enrolled. The 86 patients who experienced gastrointestinal hemorrhage during hospitalization were selected as the observation group, while the 249 remaining cases were assigned to the negative control group. The neutrophil, white blood cell and platelet count, as well as the NLR and PLR of each subject were recorded. Furthermore, sex, age, blood pressure, the site of cerebral hemorrhage, the amount of bleeding, the Glasgow Coma Scale (GCS) score and presence of hematosepsis were also recorded and assessed as potential risk factors for gastrointestinal hemorrhage in patients with acute cerebral hemorrhage. The NLR and PLR were markedly higher in the observation group compared with those in the negative control group. Furthermore, the NLR and PLR in the observation group were negatively associated with the 90-day overall survival of patients with acute cerebral hemorrhage and gastrointestinal hemorrhage. In the negative control group, only the PLR was negatively associated with overall survival. Logistic regression analysis indicated that a cerebral hemorrhage volume of >30 ml, lower GCS score and hematosepsis were independently associated with gastrointestinal hemorrhage in patients with acute cerebral hemorrhage (P<0.05). A high NLR and PLR indicated an elevated risk of gastrointestinal hemorrhage in patients with acute cerebral hemorrhage. A higher NLR and PLR were also negatively associated with overall survival and prognosis of patients with cerebral hemorrhage. In addition, a cerebral hemorrhage volume of >30 ml, lower GCS score and hematosepsis were independent risk factors of gastrointestinal hemorrhage in patients with acute cerebral hemorrhage.
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