Evidence map›Paper›PMID 31410074›Full record

ArticlePsychology research and behavior management2019

Connectivity between visual and auditory cortices mediates the influence of argument strength on the effectiveness of smoking-cessation videos among smokers low in sensation seeking.

Zhenhao Shi, An-Li Wang, Catherine A Aronowitz, Joseph N Cappella, Daniel Romer, Daniel D Langleben

Open access · goldAbstract read
In one paragraph

Article in Psychology research and behavior management, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Zhenhao ShiCenter for Studies of Addiction, Department of Psychiatry, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA 19104, USA.
An-Li WangDepartment of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.
Catherine A AronowitzAnnenberg Public Policy Center, University of Pennsylvania, Philadelphia, PA 19104, USA.
Joseph N CappellaAnnenberg School for Communication, University of Pennsylvania, Philadelphia, PA 19104, USA.
Daniel RomerAnnenberg Public Policy Center, University of Pennsylvania, Philadelphia, PA 19104, USA.
Daniel D LanglebenCenter for Studies of Addiction, Department of Psychiatry, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA 19104, USA.
University of Pennsylvania · USIcahn School of Medicine at Mount Sinai · USPhiladelphia VA Medical Center · US

Funding

T32 Translational Addiction Research Fellowship ProgramT32DA028874 · NIDA · UNIVERSITY OF PENNSYLVANIA · PI Julie A Blendy, Anna Rose Childress · 2010 to 2026
$5.0M
Brain and behavioral effects of graphic cigarette warning labelsR01DA036028 · NIDA · UNIVERSITY OF PENNSYLVANIA · PI LANGLEBEN, DANIEL D · 2013 to 2017
$2.9M
Neurobehavioral Study of Warnings for Adolescents at Risk for Nicotine DependenceR00HD084746 · NICHD · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI WANG, AN-LI · 2017 to 2019
$747k
Neurobehavioral Study of Warnings for Adolescents at Risk for Nicotine DependenceK99HD084746 · NICHD · UNIVERSITY OF PENNSYLVANIA · PI WANG, AN-LI · 2015 to 2016
$263k
NICHD NIH HHS K99 HD084746NICHD NIH HHS R00 HD084746NIDA NIH HHS R01 DA036028NIDA NIH HHS T32 DA028874
6 · The paper itself

Abstract

purposeArgument strength (AS) is a validated measure of persuasiveness that has been identified as one of the key variables determining the effectiveness of video ads. Smoking-cessation videos with high AS are more effective at reducing smoking behavior than videos with low AS. The neural processes that mediate the effects of AS on subsequent smoking have not been identified. In the present study, we tested whether the efficacy of high-AS smoking-cessation videos is determined by the level of integration of visual and auditory (ie, multisensory) processes. In addition, we tested differences in sensation seeking, which is repeatedly associated with smokers' sensitivity to cessation interventions. PATIENTS AND

methodsUsing functional magnetic resonance imaging (fMRI), we recorded the brain response of 66 smokers randomly assigned to view either 16 high-AS or 16 low-AS smoking-cessation videos. Multisensory processing was assessed by the functional connectivity between brain regions that encoded visual and auditory information in the videos. Smoking behavior was indexed by the urine level of cotinine, a nicotine metabolite, immediately before and approximately 30 days after the fMRI session.

resultsWe found a significant moderated mediation effect, such that the connectivity between visual and auditory cortices mediated the effect of AS on subsequent smoking, but only for smokers lower in sensation seeking. The prediction performance of the model was confirmed by leave-one-out cross-validation.

conclusionOur study suggests that audiovisual integration underlies the greater efficacy of high- vs low-AS smoking-cessation videos for individuals lower in sensation seeking. High-sensation-seeking smokers may be responsive to other characteristics of smoking-cessation videos.

Indexed as

brain connectivityfunctional magnetic resonance imaginghealth communicationsensation seekingsmoking

Identifiers

PMID31410074
PMCPMC6645608
OpenAlexW2957130621

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.