Evidence map›Paper›PMID 31409917›Full record

ArticleHypertension research : official journal of the Japanese Society of Hypertension2019

Augmented O-GlcNAcylation attenuates intermittent hypoxia-induced cardiac remodeling through the suppression of NFAT and NF-κB activities in mice.

Takatoshi Nakagawa, Yuichi Furukawa, Tetsuya Hayashi, Atsuo Nomura, Shunichi Yokoe, Kazumasa Moriwaki, Ryuji Kato, Yoshio Ijiri, Takehiro Yamaguchi, Yasukatsu Izumi and 2 more

Abstract read
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In one paragraph

Article in Hypertension research : official journal of the Japanese Society of Hypertension, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
0.8field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 21 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Review
  5. Review
  6. Review
  7. Review
  8. Review
  9. O-Linked β-Frontiers in immunology · 2022
    Review
  10. Regulation of cardiac O-GlcNAcylation: More than just nutrient availability.Biochimica et biophysica acta. Molecular basis of disease · 2020
    Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 1 country.

Takatoshi NakagawaDepartment of Pharmacology, Osaka Medical College, Osaka, Japan.
Yuichi FurukawaDepartment of Pharmacology, Osaka Medical College, Osaka, Japan.
Tetsuya HayashiDepartment of Pharmacology, Osaka Medical College, Osaka, Japan.
Atsuo NomuraDepartment of Pharmacology, Osaka Medical College, Osaka, Japan.
Shunichi YokoeDepartment of Pharmacology, Osaka Medical College, Osaka, Japan.
Kazumasa MoriwakiDepartment of Pharmacology, Osaka Medical College, Osaka, Japan.
Ryuji KatoDepartment of Cardiovascular Pharmacotherapy and Toxicology, Osaka University of Pharmaceutical Sciences, Osaka, Japan.
Yoshio IjiriDepartment of Cardiovascular Pharmacotherapy and Toxicology, Osaka University of Pharmaceutical Sciences, Osaka, Japan.
Takehiro YamaguchiDepartment of Cardiovascular Medicine, Osaka City University Graduate School of Medicine, Osaka, Japan.
Yasukatsu IzumiDepartment of Pharmacology, Osaka City University Graduate School of Medicine, Osaka, Japan.
Minoru YoshiyamaDepartment of Cardiovascular Medicine, Osaka City University Graduate School of Medicine, Osaka, Japan.
Michio AsahiDepartment of Pharmacology, Osaka Medical College, Osaka, Japan. masahi@osaka-med.ac.jp.
Osaka Medical and Pharmaceutical University · JPOsaka University of Pharmaceutical Sciences · JPOsaka City University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Type 2 diabetes mellitus (T

Indexed as

Ventricular RemodelingAcylationAnimalsCell LineDiabetes Mellitus, Type 2EchocardiographyGlycogen Synthase Kinase 3 betaHEK293 CellsHumansHypoxiaMiceMice, TransgenicMyocardiumN-AcetylglucosaminyltransferasesNFATC Transcription FactorsNF-kappa BGlycogen Synthase Kinase 3 betaN-AcetylglucosaminyltransferasesNFATC Transcription FactorsNF-kappa BUDP-N-acetylglucosamine-peptide beta-N-acetylglucosaminyltransferasecardiac remodelingGSK-3βNFATNF-κBO-GlcNAcylation

Identifiers

PMID31409917
OpenAlexW2967931283

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.