ArticleScientific reports2019
High-throughput metagenome analysis of the Sarcoptes scabiei internal microbiota and in-situ identification of intestinal Streptomyces sp.
Article in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed, 20 citations in OpenAlex.
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- Metagenomic Insight into the Associated Microbiome in Plasmodia of Myxomycetes.Microorganisms · 2024Article
- Scabies.Nature reviews. Disease primers · 2024Review
- Microbiota profile in organs of the horseflies (Diptera: Tabanidae) in Northeastern China.Frontiers in microbiology · 2024Article
- Sarcoptic mange changes bacterial and fungal microbiota of bare-nosed wombats (Vombatus ursinus).Parasites & vectors · 2022Article
- Microbiome diversity and reproductive incompatibility induced by the prevalent endosymbiontEcology and evolution · 2021Article
- Genome-Resolved Metagenomic Analyses Reveal the Presence of a Putative Bacterial Endosymbiont in an Avian Nasal Mite (Rhinonyssidae; Mesostigmata).Microorganisms · 2021Article
- First Description of the Composition and the Functional Capabilities of the Skin Microbial Community Accompanying Severe Scabies Infestation in Humans.Microorganisms · 2021Article
- Microbial Communities of Stored Product Mites: Variation by Species and Population.Microbial ecology · 2021Article
- Parasites of wombats (family Vombatidae), with a focus on ticks and tick-borne pathogens.Parasitology research · 2021Review
- The Management of Scabies in the 21st Century: Past, Advances and Potentials.Acta dermato-venereologica · 2020Review
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Multiple parasitic arthropods of medical importance depend on symbiotic bacteria. While the link between scabies and secondary bacterial infections causing post infective complications of Group A streptococcal and staphylococcal pyoderma is increasingly recognized, very little is known about the microbiota of Sarcoptes scabiei. Here we analyze adult female mite and egg metagenome datasets. The majority of adult mite bacterial reads matched with Enterobacteriaceae (phylum Proteobacteria), followed by Corynebacteriaceae (phylum Actinobacteria). Klebsiella was the most dominant genus (78%) and Corynebacterium constituted 9% of the assigned sequences. Scabies mite eggs had a more diverse microbial composition with sequences from Proteobacteria being the most dominant (75%), while Actinobacteria, Bacteroidetes and Firmicutes accounted for 23% of the egg microbiome sequences. DNA sequences of a potential endosymbiont, namely Streptomyces, were identified in the metagenome sequence data of both life stages. The presence of Streptomyces was confirmed by conventional PCR. Digital droplet PCR indicated higher Streptomyces numbers in adult mites compared to eggs. Streptomyces were localized histologically in the scabies mite gut and faecal pellets by Fluorescent In Situ Hybridization (FISH). Streptomyces may have essential symbiotic roles in the scabies parasite intestinal system requiring further investigation.
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