ArticleNature communications2019
Gut-associated IgA
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Article in Nature communications, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 127 papers.
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127citing papers in PubMed
8.6field-weighted citation impact, top 2% of its field
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Who cites it
127 citing papers in PubMed, 197 citations in OpenAlex.
- Rapid and long-lasting remodelling of the blood transcriptome following bariatric surgery.International journal of obesity (2005) · 2026Article
- Graph in Graph (GiG): A novel graph AI framework for integrating and interpreting medical and omics data.bioRxiv : the preprint server for biology · 2026Article
- Mechanism and therapeutic prospects of adipose tissue B lymphocytes in obesity and obesity‑associated metabolic diseases (Review).Molecular medicine reports · 2026Review
- Evaluation of immunoglobulin A1/immunoglobulin A2 ratio and B cell lymphoma-6 in relation to apoptosis-associated speck-like protein in diabetic kidney disease patients.BMC immunology · 2026Article
- Homoharringtonine exhibits senotherapeutic activity that mitigates diet- and age-associated obesity and insulin resistance and extends lifespan in mice.Nature communications · 2026Article
- Gut microbiota and metabolic disease risk in youth.Cell reports. Medicine · 2026Review
- B cells drive CD4 T cell immunosenescence and age-associated health decline.Science immunology · 2026Article
- Cerebral ischaemic stroke results in altered mucosal antibody responses and host-commensal microbiota interactions.Brain, behavior, and immunity · 2026Article
- Alterations in the gut microbiota are associated with changes in intestinal antibody production in KK-Ay mice developing type 2 diabetes.Frontiers in immunology · 2026Article
- Capsaicin attenuates high-fat diet-induced impairment of B-cell immunity.SAGE open medicine · 2026Article
- Multi-omics identifies a T2DM-associated immune-regulatory network modulated by electroacupuncture.Frontiers in endocrinology · 2026Article
- Immune activation induced by dysregulated lipid metabolism in the pathogenesis of type 2 diabetes.World journal of diabetes · 2025Review
- Short-chain fatty acids mediate interactions between immune responses and commensal bacteria in high altitude yaks.Communications biology · 2025Article
- Microbial succinate promotes the response to metformin by upregulating secretory immunoglobulin a in intestinal immunity.Gut microbes · 2025Article
- Subcutaneous white adipose tissue-derived extracellular vesicles maintain intestinal homeostasis via IgA biosynthesis in aging mice.The Journal of clinical investigation · 2025Article
- Toll-like Receptor 4 Contributes to PCOS-like Metabolic and Reproductive Pathogenesis.bioRxiv : the preprint server for biology · 2025Article
- High-fat diet, intestinal microecology and bone loss.Nutrition & metabolism · 2025Review
- The association between all-cause mortality with drinking habits and water sources: a nationwide longitudinal study on Chinese elderly.Journal of global health · 2025Article
- Comparative Analysis of Gene and MicroRNA Expression in Subcutaneous Adipose Tissue in Metabolically Healthy and Unhealthy Obesity.International journal of molecular sciences · 2025Article
- Gut-liver axis in diabetes: Mechanisms and therapeutic opportunities.World journal of gastroenterology · 2025Review
67 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
25 authors at 5 institutions in 3 countries.
Helen LuckDivision of Cellular and Molecular Biology, Diabetes Research Group, Toronto General Research Institute (TGRI), University Health Network, Toronto, ON, M5G 2C4, Canada.
Saad KhanDivision of Cellular and Molecular Biology, Diabetes Research Group, Toronto General Research Institute (TGRI), University Health Network, Toronto, ON, M5G 2C4, Canada.
Justin H KimDivision of Cellular and Molecular Biology, Diabetes Research Group, Toronto General Research Institute (TGRI), University Health Network, Toronto, ON, M5G 2C4, Canada.
Julia K CopelandCentre for the Analysis of Genome Evolution and Function, University of Toronto, Toronto, ON, M5S 3B2, Canada.
Xavier S ReveloDepartment of Integrative Biology and Physiology, University of Minnesota, Minneapolis, MN, 55455, USA.
Sue TsaiDivision of Cellular and Molecular Biology, Diabetes Research Group, Toronto General Research Institute (TGRI), University Health Network, Toronto, ON, M5G 2C4, Canada.
Mainak ChakrabortyDivision of Cellular and Molecular Biology, Diabetes Research Group, Toronto General Research Institute (TGRI), University Health Network, Toronto, ON, M5G 2C4, Canada.
Kathleen ChengDivision of Cellular and Molecular Biology, Diabetes Research Group, Toronto General Research Institute (TGRI), University Health Network, Toronto, ON, M5G 2C4, Canada.
Yi Tao ChanDivision of Cellular and Molecular Biology, Diabetes Research Group, Toronto General Research Institute (TGRI), University Health Network, Toronto, ON, M5G 2C4, Canada.
Mark K NøhrDivision of Cellular and Molecular Biology, Diabetes Research Group, Toronto General Research Institute (TGRI), University Health Network, Toronto, ON, M5G 2C4, Canada.
Xavier Clemente-CasaresDivision of Cellular and Molecular Biology, Diabetes Research Group, Toronto General Research Institute (TGRI), University Health Network, Toronto, ON, M5G 2C4, Canada.
Marie-Christine PerryDepartment of Immunology, University of Toronto, Toronto, ON, M5S 1A8, Canada.
Magar GhazarianDivision of Cellular and Molecular Biology, Diabetes Research Group, Toronto General Research Institute (TGRI), University Health Network, Toronto, ON, M5G 2C4, Canada.
Helena LeiDivision of Cellular and Molecular Biology, Diabetes Research Group, Toronto General Research Institute (TGRI), University Health Network, Toronto, ON, M5G 2C4, Canada.
Yi-Hsuan LinDivision of Cellular and Molecular Biology, Diabetes Research Group, Toronto General Research Institute (TGRI), University Health Network, Toronto, ON, M5G 2C4, Canada.
Bryan CoburnDepartment of Immunology, University of Toronto, Toronto, ON, M5S 1A8, Canada.
Allan OkrainecToronto Western Hospital, University Health Network, Toronto, ON, M5T 2S8, Canada.
Timothy JacksonToronto Western Hospital, University Health Network, Toronto, ON, M5T 2S8, Canada.
Susan PoutanenDepartment of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON, M5S 1A8, Canada.ORCID http://orcid.org/0000-0003-4747-2550
Herbert GaisanoDepartment of Medicine, University of Toronto, Toronto, ON, M5S 1A8, Canada.
Johane P AllardDepartment of Medicine, University of Toronto, Toronto, ON, M5S 1A8, Canada.
David S GuttmanCentre for the Analysis of Genome Evolution and Function, University of Toronto, Toronto, ON, M5S 3B2, Canada.ORCID http://orcid.org/0000-0001-8479-3869
Margaret E ConnerDepartment of Virology and Microbiology, Baylor College of Medicine, Houston, TX, 77030, USA.
Shawn WinerDepartment of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON, M5S 1A8, Canada.
Daniel A WinerDivision of Cellular and Molecular Biology, Diabetes Research Group, Toronto General Research Institute (TGRI), University Health Network, Toronto, ON, M5G 2C4, Canada. dan.winer@uhn.ca.
University Health Network · CAUniversity of Toronto · CABaylor College of Medicine · USSt. Michael's Hospital · CAUniversity of Minnesota · US
Funding
CIHR
Abstract
The intestinal immune system is emerging as an important contributor to obesity-related insulin resistance, but the role of intestinal B cells in this context is unclear. Here, we show that high fat diet (HFD) feeding alters intestinal IgA
Indexed as
Insulin ResistanceAdipose TissueAnimalsB-LymphocytesCohort StudiesFecesGastrointestinal MicrobiomeGlucoseHumansImmunoglobulin AIntestinesMaleMiceObesityGlucoseImmunoglobulin A
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Read underepoch 390
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.