Evidence map›Paper›PMID 31409710›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2019

The catalytic core of DEMETER guides active DNA demethylation in

Changqing Zhang, Yu-Hung Hung, Hyun Jung Rim, Dapeng Zhang, Jennifer M Frost, Hosub Shin, Hosung Jang, Fang Liu, Wenyan Xiao, Lakshminarayan M Iyer and 5 more

Open access · bronzeAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
10.5field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 47 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Base Excision DNA Repair in Plants:International journal of molecular sciences · 2023
    Review
  5. Article
  6. Comparative Seeds Storage Transcriptome Analysis ofInternational journal of molecular sciences · 2022
    Article
  7. Article
  8. Loss of Function of the RRMF Domain in OsROS1a Causes Sterility in Rice (International journal of molecular sciences · 2022
    Article
  9. DNA Methylation in Plant Responses and Adaption to Abiotic Stresses.International journal of molecular sciences · 2022
    Review
  10. Article
  11. Targeting Induced Local Lesions in the WheatFrontiers in nutrition · 2022
    Article
  12. Article
  13. Review
  14. The DME demethylase regulates sporophyte gene expression, cell proliferation, differentiation, and meristem resurrection.Proceedings of the National Academy of Sciences of the United States of America · 2021
    Article
  15. Article
  16. Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 6 institutions in 3 countries.

Changqing ZhangDepartment of Plant and Microbial Biology, North Carolina State University, Raleigh, NC 27695.
Yu-Hung HungDepartment of Plant and Microbial Biology, North Carolina State University, Raleigh, NC 27695.
Hyun Jung RimDepartment of Plant Science, Seoul National University, 08826 Seoul, Republic of Korea.
Dapeng ZhangDepartment of Biology, St. Louis University, St. Louis, MO 63103.
Jennifer M FrostDepartment of Plant and Microbial Biology, University of California, Berkeley, CA 94720.
Hosub ShinDepartment of Plant Science, Seoul National University, 08826 Seoul, Republic of Korea.
Hosung JangDepartment of Plant Science, Seoul National University, 08826 Seoul, Republic of Korea.
Fang LiuDepartment of Plant and Microbial Biology, North Carolina State University, Raleigh, NC 27695.
Wenyan XiaoDepartment of Biology, St. Louis University, St. Louis, MO 63103.
Lakshminarayan M IyerNational Center for Biotechnology Information, National Library of Medicine, National Institutes of Health, Bethesda, MD 20894.
L AravindNational Center for Biotechnology Information, National Library of Medicine, National Institutes of Health, Bethesda, MD 20894.ORCID 0000-0003-0771-253X
Xiang-Qian ZhangDepartment of Plant and Microbial Biology, North Carolina State University, Raleigh, NC 27695; aacrav@163.com rfischer@berkeley.edu huhjh@snu.ac.kr thsieh3@ncsu.edu.
Robert L FischerDepartment of Plant and Microbial Biology, University of California, Berkeley, CA 94720; aacrav@163.com rfischer@berkeley.edu huhjh@snu.ac.kr thsieh3@ncsu.edu.
Jin Hoe HuhDepartment of Plant Science, Seoul National University, 08826 Seoul, Republic of Korea; aacrav@163.com rfischer@berkeley.edu huhjh@snu.ac.kr thsieh3@ncsu.edu.ORCID 0000-0002-9367-9280
Tzung-Fu HsiehDepartment of Plant and Microbial Biology, North Carolina State University, Raleigh, NC 27695; aacrav@163.com rfischer@berkeley.edu huhjh@snu.ac.kr thsieh3@ncsu.edu.ORCID 0000-0001-7584-3721
North Carolina State University · USSeoul National University · KRNational Institutes of Health · USSaint Louis University · USUniversity of California, Berkeley · USSouth China Agricultural University · CN

Funding

Evolutionary Analysis and Comparative Genomics of Protein SuperfamiliesZIALM594244 · NLM · NATIONAL LIBRARY OF MEDICINE · PI ARAVIND, L · 2009 to 2025
$20.3M
Regulation and Function of DNA Demethylation in ArabidopsisR01GM069415 · NIGMS · UNIVERSITY OF CALIFORNIA BERKELEY · PI FISCHER, ROBERT L, ZILBERMAN, DANIEL · 2004 to 2016
$3.8M
NIGMS NIH HHS R01 GM069415
6 · The paper itself

Abstract

The

Indexed as

Catalytic DomainDNA DemethylationGene Expression Regulation, PlantArabidopsisArabidopsis ProteinsEpigenesis, GeneticEvolution, MolecularHeterochromatinModels, MolecularN-Glycosyl HydrolasesProtein BindingProtein Interaction Domains and MotifsTrans-ActivatorsArabidopsis ProteinsDEMETER protein, ArabidopsisHeterochromatinN-Glycosyl HydrolasesTrans-Activatorsactive DNA demethylationArabidopsis thalianaendosperm developmentepigenetic reprogramminggene imprinting

Identifiers

PMID31409710
PMCPMC6717269
OpenAlexW2967595161

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.