Evidence map›Paper›PMID 31409684›Full record

ArticlemBio2019

Streamlined Genetic Manipulation of Diverse

Leonor García-Bayona, Laurie E Comstock

Open access · goldAbstract read
In one paragraph

Article in mBio, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 107 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
107citing papers in PubMed, 1 pooled it
5.0field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

107 citing papers in PubMed, 1 synthesis or guideline pooled it, 179 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Article
  4. High-throughput analyses ofGut microbes · 2026
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  12. Review
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  14. Orally available designed miniproteins inhibit enterotoxigenicbioRxiv : the preprint server for biology · 2026
    Article
  15. Article
  16. Article
  17. Article
  18. A system for transferring large genetic loci inApplied and environmental microbiology · 2026
    Article
  19. Antagonism by the type VI secretion system ofProceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  20. Article

47 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Leonor García-BayonaDivision of Infectious Diseases, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA.
Laurie E ComstockDivision of Infectious Diseases, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA lcomstock@rics.bwh.harvard.edu.
Brigham and Women's Hospital · USHarvard University · US

Funding

Contact-Dependent Antagonism in Gut BacteroidalesR01AI120633 · NIAID · BRIGHAM AND WOMEN'S HOSPITAL · PI COMSTOCK, LAURIE E · 2015 to 2019
$2.1M
NIAID NIH HHS R01 AI120633
6 · The paper itself

Abstract

Studies of the gut microbiota have dramatically increased in recent years as the importance of this microbial ecosystem to human health and disease is better appreciated. The

Indexed as

Gastrointestinal MicrobiomeAnti-Bacterial AgentsBacterial ProteinsBacterial ToxinsBacteroidesBacteroidetesDrug Resistance, Multiple, BacterialGenetic EngineeringGenetic MarkersGenetic VectorsHumansInulinMetalloendopeptidasesMutationPromoter Regions, GeneticRhamnoseAnti-Bacterial AgentsBacterial ProteinsBacterial ToxinsBacteroides fragilis toxinGenetic MarkersInulinMetalloendopeptidasesRhamnoseBacteroidesmicrobiotamutant constructionvectors

Identifiers

PMID31409684
PMCPMC6692515
OpenAlexW2969197547

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.