ArticlemBio2019
The Cervicovaginal Microbiota-Host Interaction Modulates Chlamydia trachomatis Infection.
Abstract read
In one paragraph
Article in mBio, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 119 papers, 4 of them syntheses that pooled it.
0numbers the graph read from it
0cells of the map it votes in
119citing papers in PubMed, 4 pooled it
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
119 citing papers in PubMed, 4 syntheses or guidelines pooled it.
- Association Between Vaginal Microbiota and Cervical Dysplasia Due to Persistent Human Papillomavirus Infection: A Systematic Review of Evidence from Shotgun Metagenomic Sequencing Studies.International journal of molecular sciences · 2025Pooled it
- Inflammation and Stem Cell Stochasticity of HPV-induced Cervical Cancer: Epigenetics based Biomarkers through Microbiome and Metabolome for Personalized Medicine: A Systematic Review.Current medicinal chemistry · 2025Pooled it
- Lactic acid-containing products for bacterial vaginosis and their impact on the vaginal microbiota: A systematic review.PloS one · 2021Pooled it
- The Effect of Exogenous Sex Steroids on the Vaginal Microbiota: A Systematic Review.Frontiers in cellular and infection microbiology · 2021Pooled it
- Chlamydia trachomatis Incidence in Relation to Vaginal Microbiota Dynamics, Immunogenetics and Exposures in a Cohort of Young Student Women in France.The Journal of infectious diseases · 2026Trial
- Influence of dapivirine vaginal ring use on cervicovaginal immunity and functional microbiome in adolescent girls.AIDS (London, England) · 2021Trial
- Characterization of vaginal lactobacilli from South African women toward the development of a biotherapeutic to optimize the vaginal microbiome.Applied and environmental microbiology · 2026Article
- The Impact of the Vaginal Microbiome and Microbial Metabolites on HIV Transmission at the Female Reproductive Tract Epithelial Barrier.American journal of reproductive immunology (New York, N.Y. : 1989) · 2026Review
- Vaginal microbiomes and their pertinent social context: a microbial ecological review proffering AMR-STI acquisition and emergence.Biology of sex differences · 2026Review
- Integrated multi-omics analysis uncovers cervicovaginal ecological networks and their association withInfection and immunity · 2026Article
- Comparing Asymptomatic Versus Symptomatic Bacterial Vaginosis: Clinical Characteristics, Vaginal Microbiota, and Lactic Acid Profiles.Sexually transmitted diseases · 2026Article
- Multiomic analysis reveals that polyamines alter G. vaginalis-induced cervicovaginal epithelial cell dysfunction.Research square · 2026Article
- Chlamydia trachomatis orchestrates multifaceted host cell manipulation for immune evasion.Communications biology · 2026Review
- A microphysiologic human cervical model recapitulates microbial, immune, and pathogenic properties of sexually transmitted infections.Science advances · 2026Article
- Regulatory Effects ofMicroorganisms · 2026Article
- Exploring microorganism-host interactions: Emerging organoid models and analytical approaches.mLife · 2026Review
- Anti-International journal of molecular sciences · 2026Review
- The Vaginal Microbiome and Host Health: Implications for Cervical Cancer Progression.International journal of molecular sciences · 2026Review
- Epithelial polarity: a key player inmicroLife · 2026Review
- Integrating microbiome insights into cervical cancer.Frontiers in medicine · 2026Review
59 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
16 authors.
Vonetta L Edwards *Institute for Genome Sciences, University of Maryland School of Medicine, Baltimore, Maryland, USA.ORCID 0000-0002-6560-4468
Steven B Smith *Institute for Genome Sciences, University of Maryland School of Medicine, Baltimore, Maryland, USA.ORCID 0000-0003-2799-6621
Elias J McCombInstitute for Genome Sciences, University of Maryland School of Medicine, Baltimore, Maryland, USA.ORCID 0000-0001-6324-2718
Jeanne TamarelleBiostatistics, Biomathematics, Pharmacoepidemiology and Infectious Diseases, Institut Pasteur, INSERM, Université de Versailles-Saint-Quentin-en-Yvelines, Versailles, France.ORCID 0000-0003-0956-0349
Bing MaInstitute for Genome Sciences, University of Maryland School of Medicine, Baltimore, Maryland, USA.ORCID 0000-0002-3488-2393
Michael S HumphrysInstitute for Genome Sciences, University of Maryland School of Medicine, Baltimore, Maryland, USA.
Pawel GajerInstitute for Genome Sciences, University of Maryland School of Medicine, Baltimore, Maryland, USA.
Kathleen GwilliamInstitute for Genome Sciences, University of Maryland School of Medicine, Baltimore, Maryland, USA.
Alison M SchaeferDepartment of Microbiology and Immunology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.
Samuel K LaiDepartment of Microbiology and Immunology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.ORCID 0000-0003-4721-528X
Mishka TerplanDepartment of Obstetrics and Gynecology, University of Maryland School of Medicine, Baltimore, Maryland, USA.
Katrina S MarkDepartment of Obstetrics and Gynecology, University of Maryland School of Medicine, Baltimore, Maryland, USA.
Rebecca M BrotmanInstitute for Genome Sciences, University of Maryland School of Medicine, Baltimore, Maryland, USA.ORCID 0000-0001-8762-6214
Larry J ForneyDepartment of Biological Sciences, University of Idaho, Moscow, Idaho, USA.ORCID 0000-0003-2448-1219
Patrik M BavoilDepartment of Microbial Pathogenesis, University of Maryland School of Dentistry, Baltimore, Maryland, USA.ORCID 0000-0002-7340-5741
Jacques RavelInstitute for Genome Sciences, University of Maryland School of Medicine, Baltimore, Maryland, USA jravel@som.umaryland.edu.ORCID 0000-0002-0851-2233
Funding
Serologic Biomarkers of Human Sexually Transmitted Infection and DiseaseU19AI084044 · NIAID · UNIVERSITY OF MARYLAND BALTIMORE · PI KO, DENNIS CHUN-YONE · 2009 to 2018
$22.8MThe Microbial Ecology of Bacterial Vaginosis: A Fine Scale Resolution MetagenomicUH2AI083264 · NIAID · UNIVERSITY OF MARYLAND BALTIMORE · PI RAVEL, JACQUES · 2009 to 2011
$1.9MNIAID NIH HHS U19 AI084044NIAID NIH HHS UH2 AI083264
Abstract
The mechanism(s) by which
Indexed as
Cell MovementCell ProliferationCervix UteriChlamydia InfectionsChlamydia trachomatisFemaleHost Microbial InteractionsHumansHydrogen-Ion ConcentrationLactic AcidLactobacillusMicrobiotaStereoisomerismTranscriptomeVaginaLactic Acidepigeneticlactic acidLactobacillusmicrobiomeproliferationsexually transmitted infection
Identifiers
What OpenQuestion holds
Textmetadata
LicenceCC BY
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.