ArticlemSystems2019
Engineered Interspecies Amino Acid Cross-Feeding Increases Population Evenness in a Synthetic Bacterial Consortium.
Article in mSystems, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
33 citing papers in PubMed.
- Engineering an asymmetric cross-feeding consortium inSynthetic and systems biotechnology · 2026Article
- High-throughput generation and comparison of genome-scale metabolic models reveal strain-specific metabolic diversity in 439mSystems · 2026Article
- Bacteriophage-mediated cell lysis externalizes a metabolically valuable nutrient to broadly modulate bacterial communities.The ISME journal · 2026Article
- An experimental outlook on investigating temporal-scale dynamics of microbial communities.ISME communications · 2026Article
- Engineered microbes to enable a circular economy for biodegradable plastics.Frontiers in microbiology · 2026Review
- Modeling the emergent metabolic potential of soil microbiomes in Atacama landscapes.Environmental microbiome · 2025Article
- Long-term homeostasis in microbial consortia via auxotrophic cross-feeding.Nature communications · 2025Article
- Advances in synthetic microbial ecosystems approach for studying ecological interactions and their influencing factors.Engineering microbiology · 2025Review
- Review
- A data-driven modeling framework for mapping genotypes to synthetic microbial community functions.bioRxiv : the preprint server for biology · 2025Article
- Uptake and leakage rates differentially shape community arrangement and composition of microbial consortia.The ISME journal · 2025Article
- DyMMM-LEAPS: An ML-based framework for modulating evenness and stability in synthetic microbial communities.Biophysical journal · 2024Article
- Cross-feeding in the gut microbiome: Ecology and mechanisms.Cell host & microbe · 2023Review
- A Two-Compartment Fermentation System to Quantify Strain-Specific Interactions in Microbial Co-Cultures.Bioengineering (Basel, Switzerland) · 2023Article
- Public good-driven release of heterogeneous resources leads to genotypic diversification of an isogenic yeast population.Evolution; international journal of organic evolution · 2022Article
- Classifying Interactions in a Synthetic Bacterial Community Is Hindered by Inhibitory Growth Medium.mSystems · 2022Article
- Chaos in synthetic microbial communities.PLoS computational biology · 2022Article
- Stability criteria for the consumption and exchange of essential resources.PLoS computational biology · 2022Article
- Engineering microbial consortia with rationally designed cellular interactions.Current opinion in biotechnology · 2022Review
- Assembling stable syntrophic Escherichia coli communities by comprehensively identifying beneficiaries of secreted goods.Cell systems · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
12 authors.
Funding
Abstract
In nature, microbes interact antagonistically, neutrally, or beneficially. To shed light on the effects of positive interactions in microbial consortia, we introduced metabolic dependencies and metabolite overproduction into four bacterial species. While antagonistic interactions govern the wild-type consortium behavior, the genetic modifications alleviated antagonistic interactions and resulted in beneficial interactions. Engineered cross-feeding increased population evenness, a component of ecological diversity, in different environments, including in a more complex gnotobiotic mouse gut environment. Our findings suggest that metabolite cross-feeding could be used as a tool for intentionally shaping microbial consortia in complex environments.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.