Evidence map›Paper›PMID 31409625›Full record

ArticleLife science alliance2019

Kinesin-8B controls basal body function and flagellum formation and is key to malaria transmission.

Mohammad Zeeshan, David Jp Ferguson, Steven Abel, Alana Burrrell, Edward Rea, Declan Brady, Emilie Daniel, Michael Delves, Sue Vaughan, Anthony A Holder and 3 more

Abstract read
In one paragraph

Article in Life science alliance, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed.

  1. Article
  2. DivergentLife science alliance · 2025
    Article
  3. Article
  4. Microtubule inner proteins ofProceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  5. Article
  6. Article
  7. Article
  8. The molecular mechanisms driving Plasmodium cell division.Biochemical Society transactions · 2024
    Review
  9. Article
  10. Article
  11. Article
  12. mBio · 2023
    Article
  13. Characteristics of NGenomics, proteomics & bioinformatics · 2023
    Article
  14. Article
  15. Article
  16. Life science alliance · 2022
    Article
  17. Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Mohammad ZeeshanSchool of Life Sciences, Queens Medical Centre, University of Nottingham, Nottingham, UK.ORCID 0000-0002-6185-403X
David Jp FergusonDepartment of Biological and Medical Sciences, Faculty of Health and Life Science, Oxford Brookes University, Oxford, UK.ORCID 0000-0001-5045-819X
Steven AbelDepartment of Molecular, Cell and Systems Biology, University of California Riverside, Riverside, CA, USA.
Alana BurrrellDepartment of Biological and Medical Sciences, Faculty of Health and Life Science, Oxford Brookes University, Oxford, UK.ORCID 0000-0002-6067-5160
Edward ReaSchool of Life Sciences, Queens Medical Centre, University of Nottingham, Nottingham, UK.ORCID 0000-0001-9826-3981
Declan BradySchool of Life Sciences, Queens Medical Centre, University of Nottingham, Nottingham, UK.
Emilie DanielSchool of Life Sciences, Queens Medical Centre, University of Nottingham, Nottingham, UK.
Michael DelvesLondon School of Hygiene and Tropical Medicine, Keppel, London, UK.ORCID 0000-0001-8526-4782
Sue VaughanDepartment of Biological and Medical Sciences, Faculty of Health and Life Science, Oxford Brookes University, Oxford, UK.ORCID 0000-0002-0925-4491
Anthony A HolderMalaria Parasitology Laboratory, Francis Crick Institute, London, UK.ORCID 0000-0002-8490-6058
Karine G Le RochDepartment of Molecular, Cell and Systems Biology, University of California Riverside, Riverside, CA, USA.
Carolyn A MooresInstitute of Structural and Molecular Biology, Department of Biological Sciences, Birkbeck College, London, UK.
Rita TewariSchool of Life Sciences, Queens Medical Centre, University of Nottingham, Nottingham, UK rita.tewari@nottingham.ac.uk.ORCID 0000-0003-3943-1847

Funding

Chromatin structure and control of gene expression in the human malaria parasiteR01AI136511 · NIAID · UNIVERSITY OF CALIFORNIA RIVERSIDE · PI LE ROCH, KARINE GAELLE · 2018 to 2022
$3.4M
Biotechnology and Biological Sciences Research Council BB/N017609/1Biotechnology and Biological Sciences Research Council BB/N018176/1Medical Research Council G0900109Medical Research Council G0900278Medical Research Council MR/K011782/1Medical Research Council MR/N023048/1NIAID NIH HHS R01 AI136511Wellcome Trust FC001097
6 · The paper itself

Abstract

Eukaryotic flagella are conserved microtubule-based organelles that drive cell motility.

Indexed as

AnimalsAxonemeBasal BodiesFlagellaGene Expression Regulation, DevelopmentalGene TargetingKinesinsKinetochoresMalariaMicroscopy, ElectronMitosisPlasmodium malariaeKinesins

Identifiers

PMID31409625
PMCPMC6696982

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.