Evidence map›Paper›PMID 31409582›Full record

ArticleHematology, transfusion and cell therapy

Prevalence and trends in transfusion-transmissible infections among blood donors in Brazil from 2010 to 2016.

Lívia Lara Pessoni, Érika Carvalho de Aquino, Keila Correia de Alcântara

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Article in Hematology, transfusion and cell therapy. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 1 of them a synthesis that pooled it.

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29citing papers in PubMed, 1 pooled it
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

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5 · Who and what money

Authors and funding

3 authors.

Lívia Lara PessoniUniversidade Federal de Goiás (UFG), Goiania, GO, Brazil. Electronic address: liviapessoni@hotmail.com.
Érika Carvalho de AquinoUniversidade Federal de Goiás (UFG), Goiania, GO, Brazil.
Keila Correia de AlcântaraUniversidade Federal de Goiás (UFG), Goiania, GO, Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAssessing trends in the rate of transfusion-transmissible infections (TTIs) in blood donors is critical to the monitoring of the blood supply safety and the donor screening effectiveness. The objective of this study was to conduct a trend analysis of TTIs and associated demographic factors of donors at a public blood bank in the central Brazil.

methodsA retrospective analysis (2010-2016) of blood donation data was performed to determine the prevalence of markers for TTIs. Multinomial and multivariate logistic regression were used to verify the association between the explanatory variables and TTIs. The trend was evaluated with the Prais Winsten's regression analysis.

resultsThe prevalence of TTIs was 4.04% (5,553 donors) among 137,209 donors, with a steady trend in the analyzed period. The seroprevalence for the hepatitis B virus (HBV), syphilis, hepatitis C virus (HCV), human immunodeficiency virus (HIV), Chagas disease, and human T-lymphotropic virus (HTLV) were 1.63%, 0.87%, 0.46%, 0.21%, 0.21% and 0.09%, respectively. The prevalence of HBV decreased (b = -0.021, p <  0.001), while syphilis increased (b = 0.112; p =  0.001), during the period investigated. The probability for a positive test for TTI was higher among donors with a low level of education, aged ≥30 years old, without stable marital status, and first-time donors.

conclusionsEven with the reduction in HBV, the increased rate of syphilis may have contributed to the fact that the overall rate of TTIs did not decrease in the evaluated period.

Indexed as

Blood safetyEpidemiologyTransfusion medicineTransfusion-transmissible infections

Identifiers

PMID31409582
PMCPMC6978541

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.