Evidence map›Paper›PMID 31409574›Full record

ArticleEBioMedicine2019

N

Huan Jin, Xiaoling Ying, Biao Que, Xiaoxue Wang, Yinghui Chao, Haiqing Zhang, Zusen Yuan, Defeng Qi, Shuibin Lin, Wang Min and 2 more

Open access · goldAbstract read
In one paragraph

Article in EBioMedicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 141 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
141citing papers in PubMed, 1 pooled it
9.3field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

141 citing papers in PubMed, 1 synthesis or guideline pooled it, 202 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
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  5. The bladder cancer mEMBO reports · 2026
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  9. RNA modification systems as therapeutic targets.Nature reviews. Drug discovery · 2026
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  11. Unraveling the dual role of METTL3-mediated mCancer biology & therapy · 2025
    Review
  12. Article
  13. Targeting RNA adenosine editing and modification enzymes for RNA therapeutics.Molecular therapy : the journal of the American Society of Gene Therapy · 2025
    Review
  14. Review
  15. Article
  16. Article
  17. Article
  18. Epitranscriptomics Regulation of CD70, CD80, and TIGIT in Cancer Immunity.International journal of molecular sciences · 2025
    Article
  19. Review
  20. RNA mCell investigation · 2025
    Article

81 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 6 institutions in 2 countries.

Huan JinCenter for Translational Medicine, The First Affiliated Hospital, Sun Yat-sen University, 510080 Guangzhou, China; Department of Physiology, Zunyi Medical College, Guizhou 563000, China.
Xiaoling YingCenter for Translational Medicine, The First Affiliated Hospital, Sun Yat-sen University, 510080 Guangzhou, China.
Biao QueDepartment of Urology, Minimally Invasive Surgery Center, The First Affiliated Hospital of Guangzhou Medical University, Guangdong Key Laboratory of Urology, Guangzhou 510230, China.
Xiaoxue WangDepartment of Colorectal Surgery, The Sixth Affiliated Hospital of Sun Yat-sen University, Guangzhou 510655, China.
Yinghui ChaoCenter for Translational Medicine, The First Affiliated Hospital, Sun Yat-sen University, 510080 Guangzhou, China.
Haiqing ZhangCenter for Translational Medicine, The First Affiliated Hospital, Sun Yat-sen University, 510080 Guangzhou, China.
Zusen YuanDepartment of Urology, Minimally Invasive Surgery Center, The First Affiliated Hospital of Guangzhou Medical University, Guangdong Key Laboratory of Urology, Guangzhou 510230, China.
Defeng QiDepartment of Urology, Minimally Invasive Surgery Center, The First Affiliated Hospital of Guangzhou Medical University, Guangdong Key Laboratory of Urology, Guangzhou 510230, China.
Shuibin LinCenter for Translational Medicine, The First Affiliated Hospital, Sun Yat-sen University, 510080 Guangzhou, China.
Wang MinDepartment of Pathology and the Vascular Biology and Therapeutics Program, Yale University School of Medicine, New Haven, CT 06519, USA.
Mei YangDepartment of Breast Surgery, Guangdong Provincial People's Hospital, Guangzhou 510080, China. Electronic address: bayberry513@yahoo.com.
Weidong JiCenter for Translational Medicine, The First Affiliated Hospital, Sun Yat-sen University, 510080 Guangzhou, China. Electronic address: jiweidong@mail.sysu.edu.cn.
The First Affiliated Hospital, Sun Yat-sen University · CNSun Yat-sen University · CNGuangzhou Medical University · CNFirst Affiliated Hospital of Guangzhou Medical University · CNGuangdong Provincial People's Hospital · CNYale University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAccumulating evidence has revealed the critical roles of N

methodsWe performed cell phenotype analysis and established in vivo mouse xenograft models to assess the effects of m

findingsWe show that the m

interpretationOur results demonstrate an oncogenic role of m

Indexed as

AdenosineAdultAgedAlkB Homolog 5, RNA DemethylaseAnimalsCell AdhesionCell Line, TumorCell ProliferationDisease Models, AnimalDisease ProgressionFemaleGene Expression Regulation, NeoplasticHumansImmunohistochemistryIntegrin alpha6MaleAdenosineALKBH5 protein, humanAlkB Homolog 5, RNA DemethylaseIntegrin alpha6ITGA6 protein, humanMethyltransferasesMETTL3 protein, humanN-methyladenosineRNA, MessengerBladder cancerITGA6METTL3N(6)-methyladenosineProgression

Identifiers

PMID31409574
PMCPMC6796523
OpenAlexW2968332102

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.